ArticleKidney international reports2025
A Multinational Cohort Study of Dialysis Initiation During Pregnancy.
Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Nephrologist Perspectives on Navigating Pregnancy Planning and Care in Women With Kidney Disease: A Qualitative Study.Kidney medicine · 2026Article
- Severe Maternal Morbidity and Long-Term Kidney Outcomes among Pregnant Women Receiving Maintenance Dialysis.Journal of the American Society of Nephrology : JASN · 2026Article
- Dialysis During Pregnancy: Are We Any Closer to Clarity?Kidney international reports · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: There are insufficient data to guide the initiation of dialysis in pregnancy, contributing to wide variation in practice and uncertainty in the management of this high-risk population. Our study aimed to examine dialysis initiation patterns in pregnancy, describe adverse pregnancy outcomes in women with advanced chronic kidney disease (CKD), and assess the impact of dialysis hours on these outcomes. Methods: We conducted a multinational retrospective cohort study of women who delivered between January 1, 2000 and October 31, 2022. Eligible women had either a prepregnancy estimated glomerular filtration rate (eGFR) <30 ml/min per 1.73 m Results: A total of 169 pregnancies in 149 women were included; 79 (46.7%) initiated dialysis during pregnancy at a median of 21.4 weeks' gestation (interquartile range [IQR]: 13.3-25.0). There were regional differences in dialysis initiation and dose (hours/wk). Adverse maternal and fetal outcomes were more frequent in women who started dialysis during pregnancy. No significant associations were observed between dialysis hours/wk and adverse maternal and fetal outcomes. At 1 year postpartum, the mean change in eGFR compared with prepregnancy values in nondialyzed women was -8.4 ml/min per 1.73 m Conclusion: Advanced CKD poses significant maternal and fetal risks during pregnancy, often necessitating dialysis initiation. Variations in clinical practice underscore the need for standardized care in this high-risk population.
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