Evidence map›Paper›PMID 40677278›Full record

ArticleACG case reports journal2025

Leave No "Stone" Unturned: Biliary Obstruction From Isolated Intraductal Metastatic HCC.

Shivani Desai, Katrina A McGinty, Andrew Canakis, Lee-Ching Zhu, Neil D Shah

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shivani DesaiUniversity of North Carolina School of Medicine, Chapel Hill, NC.ORCID https://orcid.org/0009-0006-3553-3992
Katrina A McGintyDepartment of Radiology, University of North Carolina, Chapel Hill, NC.
Andrew CanakisDivision of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, NC.
Lee-Ching ZhuDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC.
Neil D ShahDivision of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) metastases to the biliary tree are exceedingly rare. We present a patient with hepatitis C virus (HCV) cirrhosis and recurrent HCC treated previously by locoregional therapy, who presented for Y-90 embolization but was found to have obstructive jaundice. Intraductal biopsy confirmed isolated, metastatic HCC in the distal common bile duct leading to obstruction. Albeit rare, bile duct metastases should be considered in patients with HCC treated by locoregional therapy presenting with obstructive jaundice. To our knowledge, this is the first report of metastatic HCC to the common bile duct in a patient who has not undergone prior partial hepatectomy.

Indexed as

biliary metastaseshepatocellular carcinomalocoregional therapy

Identifiers

PMID40677278
PMCPMC12269809

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.