Evidence map›Paper›PMID 40677259›Full record

ArticleData in brief2025

Dataset of pharmacotherapy in autism spectrum disorder.

Sebastião Gonçalves de Barros Neto, Catherine Oliveira de Araújo, Renandro de Carvaho Reis, Kelson James da Silva Almeida, Decio Brunoni, Roberta Monterazzo Cysneiros

Abstract read
In one paragraph

Article in Data in brief, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sebastião Gonçalves de Barros NetoLaboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 - prédio 28, 10 andar - São Paulo- SP, CEP 04048061, Brazil.
Catherine Oliveira de AraújoLaboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 - prédio 28, 10 andar - São Paulo- SP, CEP 04048061, Brazil.
Renandro de Carvaho ReisPharmaceutical Science Postgraduate Program. Federal University of Piaui. Teresina - PI, Brazil.
Kelson James da Silva AlmeidaPharmaceutical Science Postgraduate Program. Federal University of Piaui. Teresina - PI, Brazil.
Decio BrunoniLaboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 - prédio 28, 10 andar - São Paulo- SP, CEP 04048061, Brazil.
Roberta Monterazzo CysneirosLaboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 - prédio 28, 10 andar - São Paulo- SP, CEP 04048061, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmacological interventions are widely used in autism spectrum disorder (ASD). We investigated the profile of psychopharmaceutical in a sample of children with ASD of low socioeconomic stratum enrolled and the public school in the city of Embu das Artes, Sao Paulo Brazil. From 149 children with a diagnosis of ASD identified in the municipal education department, informant consents were obtained from 129 children's parents. Data collection was performed through clinical evaluation of the children and face to face application of a questionnaire for parents regarding medication use. The participants socioeconomic stratum was mostly C (72.86 %), followed by B (16,27 %), D (10.07 %), and A (0.7 %) who do not undergo specialized multi-professional educational and behavioral intervention. Among the participants 57.36 % were under psychopharmacological intervention and 33.78 % were under a polypharmacy regimen. Typical antipsychotics were used for 35.4 % followed by atypical antipsychotics (27.43 %), antiseizure (19.47 %), and tricyclic antidepressants (7.08 %). The association of risperidone with valproic acid prevailed in 17.68 % of the sample. ASD levels 2 and 3, epilepsy and age were associated with a higher rate of psychopharmaceutical use. The present dataset can be used to investigate the rational use of medication in the ASD population to monitor potential adverse effects, and to compare with the ASD population across the world

Indexed as

AgeAutism spectrum disorderEpilepsyMedicationPsychopharmaceutical

Identifiers

PMID40677259
PMCPMC12269430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.