Evidence map›Paper›PMID 40676999›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2025

Site-selective arylations of nature-inspired flavonoids or steroidal phenols

Rebeka Ignácz, Noémi Bózsity, Dénes Unger, Zoltán Kele, István Zupkó, Attila Hunyadi, Marija Gjorgoska, Tea Lanišnik Rižner, Erzsébet Mernyák

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rebeka IgnáczInstitute of Pharmacognosy, University of Szeged, Szeged, Hungary.
Noémi BózsityInstitute of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary.
Dénes UngerInstitute of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary.
Zoltán KeleDepartment of Medicinal Chemistry, University of Szeged, Szeged, Hungary.
István ZupkóInstitute of Pharmacodynamics and Biopharmacy, University of Szeged, Szeged, Hungary.
Attila HunyadiInstitute of Pharmacognosy, University of Szeged, Szeged, Hungary.
Marija GjorgoskaInstitute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Tea Lanišnik RižnerInstitute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Erzsébet MernyákInstitute of Pharmacognosy, University of Szeged, Szeged, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenols are important structural elements of natural products and pharmaceuticals. Due to their versatile chemical transformability, phenols are frequently used building blocks in medicinal chemistry. Their aromatic nature allows directed C(sp

Indexed as

Antineoplastic AgentsFlavonoidsPhenolsSteroidsCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHeLa CellsHumansMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsFlavonoidsPhenolsSteroids13α-oestroneanticancerarylationdiaryliodonium saltprotoflavone

Identifiers

PMID40676999
PMCPMC12278462

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.