Evidence map›Paper›PMID 40676788›Full record

ReviewCurrent topics in medicinal chemistry2025

Microalgae and Human Disorders: Mechanistic Insights and Therapeutic Potential.

Santheraleka Ramanathan, Hemamalini Rawindran, Subash C B Gopinath, Chai Pui Van

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current topics in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Santheraleka RamanathanDepartment of Chemical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0002-3991-4382
Hemamalini RawindranDepartment of Chemistry, Faculty of Science, Centre for Sustainable Nanomaterials, Ibnu Sina Institute for Scientific and Industrial Research, Universiti Teknologi Malaysia, 81310, Johor Bahru, Johor, Malaysia.
Subash C B GopinathCenter for Global Health Research, Saveetha Medical College & Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai - 602 105, Tamil Nadu, India.
Chai Pui VanDepartment of Chemical and Petroleum Engineering, Faculty of Engineering, UCSI University, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microalgae, which are primarily autotrophic organisms, have caught the spotlight due to their impressive growth rates and broad distribution. They're particularly exciting because of their biocompatibility and the wide range of biological activities they offer. Species like Spirulina and Chlorella exhibit high antioxidant, anti-inflammatory, antimicrobial, anticancer, antihypertensive, anti-lipidemic, and anti-diabetic properties, making them a promising element in therapeutics. This review discusses the bioactive compounds present in microalgae, including peptides, polysaccharides, and lipids, and their mechanisms of action in disease diagnosis and prognosis. In addition, emerging reports on the synergistic effects of microalgae bioactive compounds in enhancing immune and gut health are discussed. Despite this, challenges in the extraction, cultivation, and commercialization of microalgae-based bioactive compounds remain significant hurdles for a great extent of application. This review examines the challenges and proposes relevant approaches to improve bioavailability and to optimize the cultivation of microalgae. The review underscores the significance of microalgae-derived bioactive agents for pharmaceutical and biomedical applications.

Indexed as

MicroalgaeAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsHumansPolysaccharidesAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsPolysaccharidesBioactive compoundsBioavailabilityBiomedical applicationsHealth-promotingMicroalgaePharmaceutical

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.