Evidence map›Paper›PMID 40676715›Full record

ArticleThoracic cancer2025

Surgical Outcomes of Video-Assisted Thoracic Surgery Combined With Computed Tomography-Guided Microwave Ablation for Lung Cancer Presenting as Multiple Ground-Glass Opacities: A 5-Year Retrospective Cohort Study.

Bin Huang, Chuanfei Zhan, Pengcheng Yu, Yifan Xu, Muhammad Zunair Bhatti, TianMing Chen, WenDa Yin, Zhifei Ma, Chi Su, Zhongqiu Wang and 6 more

Erratum issuedAbstract read
In one paragraph

Article in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Bin HuangDepartment of Radiotherapy, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0002-7738-3455
Chuanfei ZhanDepartment of Crirical Care Unit, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Pengcheng YuDepartment of Thoracic Surgery, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Yifan XuNeurosurgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Muhammad Zunair BhattiDepartment of Thoracic Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
TianMing ChenDepartment of General Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
WenDa YinDepartment of Radiation Oncology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, China.
Zhifei MaDepartment of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Chi SuDepartment of Thoracic Surgery, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Zhongqiu WangDepartment of Thoracic Surgery, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Dongjie FengDepartment of Thoracic Surgery, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Tian ShenDepartment of Pathology, Nanjing Medical University Affiliated Nanjing Hospital (Nanjing First Hospital), Nanjing, China.
Xiaokang ShenDepartment of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Dongqing LuDepartment of Oncology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Lin ZhengDepartment of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Shilin ChenDepartment of Thoracic Surgery, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.

Funding

China Postdoctoral Science Foundation 2018M642199Social Development Projects in Jiangsu Province BE2017758
6 · The paper itself

Abstract

backgroundMultiple ground glass opacities (mGGOs) are frequently observed in patients with early-stage lung adenocarcinoma. The most appropriate and effective treatment for these mGGOs remains controversial. The purpose of this study was to retrospectively review the usefulness and safety of performing video-assisted thoracic surgery (VATS) combined with computed tomography (CT)-guided microwave ablation (MWA) in patients with synchronous multiple primary lung cancer (sMPLC) and to demonstrate the long-term surgical outcomes at our institute. MATERIALS AND

methodsFrom April 2019 to December 2021, we enrolled 47 patients who underwent VATS combined with CT-guided MWA for mGGOs. Comprehensive data regarding the enrolled subjects, including clinical features, imaging findings, histopathological characteristics, and surgical records, were meticulously extracted from the surgical database and electronic medical records. The outcomes assessed in this study included the feasibility and safety profile of the combined procedure, as well as event-free survival (EFS), local progression-free survival (LPFS), and overall survival (OS).

resultsA total of 47 patients with sMPLC characterized by mGGOs underwent VATS combined with CT-guided MWA. In this cohort, 173 GGOs were removed, including 69 nodules (39.9%) larger than 8 mm and 104 nodules (60.1%) measuring between 5 and 8 mm. We recorded all 58 types of VATS surgeries performed on 83 nodules. Additionally, 90 secondary nodules were treated with CT-guided MWA during either a single hospitalization or multiple hospitalizations (ranging from 1 to 4). We achieved a 100% technical success rate among the 47 patients. During the follow-up, there was no local tumor progression or recurrence among the 47 patients. Event-free survival was 100% at 3 years and 66.82% at 5 years, and the 5-year overall survival rate was 97.5%, with only one patient dying from an unrelated cause.

conclusionVATS combined with CT-guided MWA is a safe and effective method for patients with mGGOs. This combination marks the onset of an era where surgeons can utilize both a needle and a scalpel simultaneously.

Indexed as

Lung NeoplasmsMicrowavesSurgery, Computer-AssistedThoracic Surgery, Video-AssistedTomography, X-Ray ComputedAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomemicrowave ablationmultiple ground–glass opacitiesretrospective cohort studysynchronous multiple primary lung cancervideo‐assisted thoracic surgery

Identifiers

PMID40676715
PMCPMC12270821

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.