Evidence map›Paper›PMID 40676637›Full record

Trial reportJournal of physiological anthropology2025

A study on the effect of acute hyperbaric oxygen intervention on aerobic endurance.

Zepeng Hu, Wenjing Guo, Hao Wu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of physiological anthropology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zepeng HuSchool of Sport Science and Health, Capital University of Physical Education and Sports, Beijing, 100191, China.
Wenjing GuoSchool of Sport Science and Health, Capital University of Physical Education and Sports, Beijing, 100191, China.
Hao WuSchool of Sport Science and Health, Capital University of Physical Education and Sports, Beijing, 100191, China. 14008001033@cupes.edu.cn.

Funding

National Key Research and Development Program ;Emerging Interdisciplinary Platform for Medicine and Engineering in Sports 2018YFF0300603, 2018YFF0300902,11000024210200089230-XM001
6 · The paper itself

Abstract

introductionThis study aimed to explore the effects of a single mild-dose, acute hyperbaric oxygen (HBO) intervention (1.3 ATA, 100% oxygen, 60 min) on aerobic endurance, cardiac function, pulmonary function, and autonomic nervous system balance in healthy young men.

methodsUsing a randomized crossover design, 14 participants received both the HBO intervention and the control condition (seated rest). For each condition, heart rate variability (HRV), cardiac function, and pulmonary function were assessed before and after the intervention, while aerobic endurance indicators-such as peak oxygen uptake (VO₂peak) and time to exhaustion (TTE)-were measured once following each condition.

resultsHBO significantly decreased resting heart rate (from 63.64 ± 7.75 to 58.79 ± 7.29 bpm, Δ = -7.23%, p = 0.009), with a significant main effect of time (F(1,13) = 7.657, p = 0.016, η

conclusionA single mild-dose, acute HBO intervention can significantly improve resting heart rate and enhance short-term HRV parameters, suggesting a beneficial effect on parasympathetic activity. However, it does not directly enhance aerobic endurance, and long-term interventions or combined training may be needed to realize its potential benefits.

Indexed as

ExerciseHyperbaric OxygenationPhysical EnduranceAdultAutonomic Nervous SystemCross-Over StudiesHeart RateHumansMaleOxygen ConsumptionYoung AdultAerobic enduranceCardiac outputExercise performanceHeart rate variabilityHyperbaric oxygenPulmonary function

Identifiers

PMID40676637
PMCPMC12273222

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.