Evidence map›Paper›PMID 40676534›Full record

ArticleBMC public health2025

Awareness and acceptability of long-acting injectable pre-exposure prophylaxis for HIV prevention among female students at tertiary learning institutions: a multi-center, institution-based cross-sectional study.

Martin Kampamba, Pumulo Munawai, Remmy Sioma, Christabel Mwila Hikaambo, Steward Mudenda, Mukumbi Mutenda, Jean M Mukumbuta, Muchindu Hampango, Muzyamba Malambo, Gunet Mwalungali and 5 more

Abstract readMulticenter Study
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Martin KampambaSchool of Health Sciences, Department of Pharmacy, University of Zambia, Lusaka, Zambia. martin.kampamba@unza.zm.
Pumulo MunawaiSchool of Health Sciences, Department of Pharmacy, University of Zambia, Lusaka, Zambia.
Remmy SiomaSchool of Health Sciences, Department of Pharmacy, University of Zambia, Lusaka, Zambia.
Christabel Mwila HikaamboSchool of Health Sciences, Department of Pharmacy, University of Zambia, Lusaka, Zambia.
Steward MudendaSchool of Health Sciences, Department of Pharmacy, University of Zambia, Lusaka, Zambia.
Mukumbi MutendaDepartment of Pharmacy, Children's Hospital, University Teaching Hospitals, Lusaka, Zambia.
Jean M MukumbutaDepartment of Pharmacy, Livingstone University Teaching Hospital, Livingstone, Zambia.
Muchindu HampangoDepartment of Pharmacy, Boitekanelo College, Gaborone, Botswana.
Muzyamba MalamboDepartment of Pharmacy, Women and New-born Hospital, University Teaching Hospitals, Lusaka, Zambia.
Gunet MwalungaliSchool of Medicine, Cavendish University, Lusaka, Zambia.
Audrey HamachilaSchool of Health Sciences, Department of Pharmacy, University of Zambia, Lusaka, Zambia.
Billy ChabalengeDepartment of Medicines Control, Zambia Medicines Regulatory Authority, Lusaka, Zambia.
Jimmy HangomaDepartment of Pharmacy, School of Health Sciences, Levy Mwanawasa Medical University, Lusaka, Zambia.
Mashebe Innocent NgulaSchool of Health Sciences, Department of Pharmacy, University of Zambia, Lusaka, Zambia.
Bernard AppiahResearch Program on Health Communication and Public Engagement, Department of Public Health, Syracuse University, 13224, Syracuse, NY, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescent girls and young women (AGYW) in Zambia face an elevated risk of acquiring HIV. Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is an effective scientific method to prevent new HIV infections. However, awareness and acceptability of LAI-PrEP among AGYW remain limited. Thus, we aimed to assess awareness and acceptability of LAI-PrEP among female students.

methodsThis multi-center, institution-based cross-sectional study involved 760 female students from three universities in Lusaka, Zambia. Data were collected using a structured, self-administered questionnaire. Questions on acceptability and awareness were presented in a yes/no format. Data analysis was performed using STATA version 15.1.

resultsOf the 760 participants, less than half, 349 (45.9%), were aware of injectable PrEP, with lectures being the most common source of information. In terms of acceptability, 531 (69.9%) of respondents indicated they would be willing to take LAI-PrEP once available. Biomedical science students were significantly less likely to accept injectable PrEP (AOR = 0.10, CI: 0.01-0.94, p = 0.044), as were those not at risk of HIV in the past three months (AOR = 0.41, CI: 0.21-0.81, p = 0.011). Conversely, knowing a partner's HIV status (AOR = 2.52, CI: 1.27-4.98, p = 0.0001) and being at risk of HIV in the past three months (AOR = 3.4, CI: 1.78-7.81, p = 0.011) were significantly associated with LAI-PrEP acceptability.

conclusionThe study revealed a notable gap in awareness of LAI-PrEP among participants, with less than half being informed about its existence. Despite this low awareness, a significant majority expressed a willingness to accept LAI-PrEP if it were made available to them. This indicates a strong potential for adoption of LAI-PrEP, contingent upon improved education and awareness efforts.

Indexed as

Anti-HIV AgentsHealth Knowledge, Attitudes, PracticeHIV InfectionsPatient Acceptance of Health CarePre-Exposure ProphylaxisStudentsAdolescentAdultCross-Sectional StudiesFemaleHumansInjectionsSurveys and QuestionnairesUniversitiesYoung AdultZambiaAnti-HIV AgentsAcceptabilityAwarenessHIVLong-acting injectabPre-exposure prophylaxisPrEP

Identifiers

PMID40676534
PMCPMC12269260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.