ArticleOdontology2026
Antibacterial activity of a bioactive composite resins containing surface pre-reacted glass in a complex multispecies subgingival biofilm.
Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Bioactive Fillers in Bulk-Fill Composite Resins: A Comprehensive Review of the Effects on Polymerization Shrinkage Behavior and Mechanical Performance.Materials (Basel, Switzerland) · 2026Review
- Biological Effects on S-PRG: An Integrative Review.Journal of functional biomaterials · 2026Review
- Current Developments in Antibacterial Nanoparticle-Based Dental Composite Materials: A Comprehensive Overview.International journal of dentistry · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
This study evaluated the antibacterial activity of three S-PRG composite resins on the microbial profile of subgingival multispecies biofilm. A 96-well cell plate was employed to cultivate a 39-species biofilm associated with periodontitis over 7 days. Cylindrical specimens with 2 mm high and 2 mm diameters were prepared of each bioactive tested group (Beautifil II, Beautifil LS, Beautifil Bulk-Shofu) and for a control non-bioactive group (Z350 XT-3M ESPE). Furthermore, these specimens were immersed in the well plate to allow biofilm formation, and after growing for 7 days, the formed biofilm was removed and composition evaluated. The metabolic biofilm activity was evaluated by colorimetric assay, and the microbial profile evaluated by DNA-DNA hybridization. Statistical analysis was performed by Kruskal-Wallis followed by Mann-Whitney tests to evaluate each bacteria counts and ANOVA followed by T test to evaluate the proportion among complexes groups. A statistically significant reduction was observed on the counts of biofilm bacterial specie: Streptococcus gordoni, Streptococcus mitis, Streptococcus sanguinis, Campylobacter rectus, Campylobacter showae, Fusobacterium periodonticum, Tannerella forsythia, Neisseria mucosa, Selenomonas noxia and Streptococcus mutans for one or more bioactive composite resin compared to Z350XT (p ≤ 0.05). There was a significant reduction in the proportion of Yellow, Orange bacterial complexes, and others oral bacteria tested between the control and bioactive groups. Bioactive groups showed a statistically significant reduction in total counts of bacteria. The incorporation of S-PRG glass into the bioactive composite resin reduced periodontopathogenic biofilm growth.
Indexed as
Identifiers
40676445What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.