Observational studyClinical and experimental nephrology2025
Estimated T50 calciprotein crystallization test in patients undergoing hemodialysis: Osaka Dialysis Complication Study (ODCS).
Observational study in Clinical and experimental nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- ABO Blood Types and Mortality in Patients Undergoing Hemodialysis.Kidney international reports · 2026Article
- Inverse Association between T50 Calciprotein Crystallization (Serum Calcification Propensity) and Carotid Artery Intima-Media Thickness in Health Examinees with a Reduced Kidney Function.Journal of atherosclerosis and thrombosis · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
Abstract
backgroundT50 calciprotein crystallization test (serum calcification propensity, T50) is a blood test which assesses the resistance of the serum to calcification stress in vitro. Because of its limited availability in clinical practice of chronic kidney disease, we aimed to develop equations for estimated T50 (eT50).
methodsThis was an observational study in 1,651 hemodialysis patients whose T50 was measured by the method Pasch et al. The data sets were divided into two groups for the derivation (N = 1,003) and validation (N = 648) of the equations. Logarithmically transformed values of measured T50 were regressed by relevant variables selected from 36 candidates based on the Akaike's Information Criteria.
resultsBecause the initial model A included 19 variables, we developed simpler models B and C with 10 and 5 variables, respectively, for clinical use. All these models included serum phosphate, magnesium, sodium, chloride, and total ion binding capacity. When these equations were validated, the intercept, slope, and R
conclusionsWe developed three equations for eT50 from clinically available variables. These eT50 values may be useful if measured T50 is not available.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.