Evidence map›Paper›PMID 40676315›Full record

ArticleEJNMMI radiopharmacy and chemistry2025

Auger electron-emitting EGFR-targeted and non-targeted [

Madeline K Brown, Zhongli Cai, Constantine J Georgiou, Shaohuang Chen, Yumeela Ganga-Sah, Valery Radchenko, James T Rutka, Raymond M Reilly

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Panitumumab labeled with Auger electron-emittingEJNMMI radiopharmacy and chemistry · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Madeline K BrownDepartment of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Zhongli CaiDepartment of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Constantine J GeorgiouDepartment of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.
Shaohuang ChenLife Sciences Division, TRIUMF, Vancouver, BC, Canada.
Yumeela Ganga-SahLife Sciences Division, TRIUMF, Vancouver, BC, Canada.
Valery RadchenkoLife Sciences Division, TRIUMF, Vancouver, BC, Canada.
James T RutkaDivision of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada.
Raymond M ReillyDepartment of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada. raymond.reilly@utoronto.ca.ORCID http://orcid.org/0000-0003-1038-7993

Funding

Canadian Cancer Society Innovation GrantCentre for Pharmaceutical Oncology ScholarshipCIHR Project GrantGovernment of Ontario Ontario Graduate ScholarshipLeslie Dan Faculty of Pharmacy, University of Toronto MDS-Nordion Scholarship in Radiopharmaceutical SciencesNational Research Council of Canada Supporting FundsNFRF-T Transformation GrantNFRF-T Transformaton GrantNSERC CREATE Training Program in Polymer Nanoparticles for Drug Delivery (POND)NSERC Discovery GrantPfizer Canada Graduate FellowshipSTARS21 Scholarship
6 · The paper itself

Abstract

backgroundWe describe here radiation nanomedicines for glioblastoma multiforme (GBM) composed of gold nanoparticles (AuNPs) that integrate the Auger electron-emitter,

results[

conclusionRadiation nanomedicines incorporating the AE-emitter,

Indexed as

197HgAuger electronsConvection-enhanced deliveryEpidermal growth factor receptors (EGFR)Glioblastoma multiforme (GBM)Gold nanoparticlesPanitumumab

Identifiers

PMID40676315
PMCPMC12271031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.