Trial reportScientific reports2025
Effectiveness of short-term cycling interventions in older adults: a randomized trial of hypoxic, blood flow restriction, and eccentric cycling.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Remote coaching with blood flow restriction training: impact on strength, body composition, metabolism, and walking energetics in overweight adults.European journal of applied physiology · 2026Article
- A bacterial enzyme enhances both energy metabolism and health across the life span ofScience advances · 2026Article
- Health Benefits of Cycling as a Form of Active Travel: A Pilot Empirical Study.International journal of environmental research and public health · 2026Article
- Effects of individualized blood flow restriction during brief twice-weekly low-load cycling on mobility and muscle function in adults older than 70 years.Frontiers in sports and active living · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
We evaluated whether a short-term cycling intervention in hypoxia, with blood flow restriction, or eccentric cycling induces greater health benefits than traditional cycling in older adults. Fifty-five individuals (68 ± 4 year, 25 females) performed supervised moderate-intensity intermittent training (MIIT) three times weekly for 4 weeks, assigned to one of four groups: HYP (hypoxic chamber, FiO₂ 14%), BFR (thigh cuffs at ≈ 350 mmHg, deflated between sets), ECC (eccentric ergocycle), or CON (traditional ergocycle). Pre- and post-training assessments covered cardiovascular function, quality of life, cognition, aerobic fitness, skeletal muscle oxidative capacity, knee extensors and flexors strength, and thigh volume. Training interventions improved the 6-min cycling test average power output (9 ± 15%, P < 0.001), isokinetic at different speeds (10 ± 16 to 20 ± 26%, all P < 0.001) and isometric peak torques (14 ± 15%, P < 0.001), thigh circumference (1 ± 2%, P = 0.008), diastolic pressure (-3 ± 8%, P = 0.021), resting heart rate (-3 ± 7%, P = 0.004), digit span (9 ± 21%, P = 0.031) and TMT-B performance (-1 ± 51%, P = 0.045) in all groups. However, no significant differences were observed between groups. These results confirm the efficacy of MIIT in older adults and suggest that exercise per se is more important than the specific modalities. Short-term (4-week) MIIT programs promote healthy aging, regardless of the training modality, which may encourage older adults to take action.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.