ArticleScientific reports2025
Broadband time domain diffuse optical characterization of human cadaver bone from 500 to 1100 nm.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Development of solid-state fluorescence lifetime standards for clinical applications using dyed epoxy resins.Journal of biomedical optics · 2026Article
- From Simulation to Therapy: Light Guidance Through Zirconium Dental Implants for Bone-Targeted Photodynamic Inactivation.Bioengineering (Basel, Switzerland) · 2026Article
- In-vivo optical properties spectra across five body locations on ten subjects using time-domain diffuse optics.Scientific data · 2026Article
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Authors and funding
8 authors.
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Abstract
Bone is an integral component of the skeletal system, providing structural support and playing a crucial role in metabolic and pathological processes. Understanding its optical properties is essential for uncovering its structural heterogeneity and biochemical composition. However, the optical properties evaluation and biomarker decomposition is challenging due to its highly scattering nature. In this study, we present the optical characterization of fresh cadaveric human tibia bone from an 89-year-old female donor using Time-Domain Diffuse Optical Spectroscopy (TDDOS) technique. Absorption and reduced scattering spectra were obtained at three distinct locations of the tibia, revealing characteristic absorption peaks corresponding to key biomarkers such as oxy-haemoglobin (HbO
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