ReviewTrends in biochemical sciences2025
Molecular mimicry: ecology, evolution, and applications of doppelgänger peptides.
Review in Trends in biochemical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Toxins in disguise: Neuropeptide mimicry across animal venoms.General and comparative endocrinology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Organisms engage in chemical interactions that drive cooperation, conflict, natural selection, and adaptation. Among these, doppelgänger peptides (molecular mimics of the endogenous hormones or neuropeptides of another organism) have evolved in many venomous and poisonous organisms, and some parasites and pathogens. While the discovery of these peptides has been largely anecdotal, a surge in sequence data combined with computational tools suggests they are more prevalent than previously recognized. Beyond their significance in biology, emerging techniques for studying cellular signaling and a renewed interest in peptide-based therapeutics position these molecules as candidates for translational applications. In this review, we explore the role of doppelgänger peptides in chemical ecology, molecular evolution, and medicine, and provide new perspectives to guide future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.