Evidence map›Paper›PMID 40675642›Full record

ArticleBMJ open2025

Effectiveness of predictive scoring systems in predicting mortality in relation to baseline kidney function in adult intensive care unit patients: a systematic review protocol.

Hajar El Wadia, Amos Buh, Abdulghani Omar Kabli, Marisha Karim, Nandini Biyani, Risa Shorr, Inok Lee, Edward G Clark, Ayub Akbari, Greg Knoll and 1 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hajar El WadiaUniversity of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada helwa093@uottawa.ca.ORCID http://orcid.org/0009-0007-0892-4530
Amos BuhClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-0732-4193
Abdulghani Omar KabliClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Marisha KarimClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Nandini BiyaniClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Risa ShorrLearning Services, Ottawa Hospital, Ottawa, Ontario, Canada.
Inok LeeUniversity of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.
Edward G ClarkDepartment of Medicine, University of Ottawa, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-6767-1197
Ayub AkbariUniversity of Ottawa, Ottawa, Ontario, Canada.
Greg KnollUniversity of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.
Gregory L HundemerClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0003-3559-3531

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPredictive scoring systems support clinicians in decision-making by estimating the prognosis of patients in intensive care units (ICUs). However, there is limited evidence on the accuracy of these systems in predicting mortality and organ dysfunction in special populations. The aim of this review is to assess the performance of predictive scoring systems in forecasting mortality in adult ICU patients in relation to baseline kidney function. It is anticipated that the assessment of predictive scoring systems' performance and patient outcomes in this review may reveal information that will contribute to improve the quality of care and outcomes for special or under-represented ICU patient populations. It might also inform future research and contribute to the development of novel risk prediction models to address identified gaps or unanswered questions. METHODS AND ANALYSIS: This review will include only observational studies, as these allow us to assess the real-world performance of predictive scoring systems in ICU settings by examining the original validation studies. By excluding randomised trials, paediatric studies, case reports and machine learning-derived models, this review focuses on the direct practical use of the scoring systems in adult ICU patients. A comprehensive search of MEDLINE, Embase and Scopus was conducted from database inception to 10 October 2024. The data will be extracted on study characteristics, patient outcomes and performance metrics. ETHICS AND DISSEMINATION: This review will analyse data from previously published studies; no ethical approval is required. All data that will be included in the analysis will be publicly available and will be included in the final manuscript. Results will be disseminated through publication in a peer-reviewed journal and will also be presented at seminars and conferences. PROSPERO REGISTRATION NUMBER: CRD42024611547.

Indexed as

Hospital MortalityIntensive Care UnitsKidneyAdultHumansOrgan Dysfunction ScoresPrognosisResearch DesignRisk AssessmentSystematic Reviews as TopicAdult intensive & critical careChronic renal failureMortalityNephrologySystematic Review

Identifiers

PMID40675642
PMCPMC12273111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.