Evidence map›Paper›PMID 40674638›Full record

ArticleChemistry & biodiversity2025

Efficient Extraction of Phenolic Compounds From Cariniana rubra Gardener Ex Miers From the Legal Amazon: Ultrasound-Assisted Optimization, Chemical Characterization, and Antioxidant Potential.

Aline Biggi Maciel, Elis Ramos de Queiroz Jácome, Naísa Andrade da Silva, Rachel de Moura Nunes Fernandes, Claudia Andrea Lima Cardoso, Elisandra Scapin

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aline Biggi MacielGraduate Program in Biodiversity and Biotechnology-BIONORTE, Federal University of Tocantins, Palmas Campus, Palmas, Tocantins, Brazil.ORCID https://orcid.org/0000-0002-0623-2297
Elis Ramos de Queiroz JácomeLaboratory of Teaching and Research in Natural Products and Biomass, Federal University of Tocantins, Palmas, Tocantins, Brazil.
Naísa Andrade da SilvaLaboratory of Teaching and Research in Natural Products and Biomass, Federal University of Tocantins, Palmas, Tocantins, Brazil.
Rachel de Moura Nunes FernandesChemistry Laboratory, Federal University of Tocantins, Palmas, Tocantins, Brazil.ORCID https://orcid.org/0000-0002-4524-8961
Claudia Andrea Lima CardosoCenter For Studies in Natural Resources, State University of Mato Grosso Do Sul, Dourados, Mato Grosso do Sul, Brazil.ORCID https://orcid.org/0000-0002-4907-0056
Elisandra ScapinGraduate Program in Biodiversity and Biotechnology-BIONORTE, Federal University of Tocantins, Palmas Campus, Palmas, Tocantins, Brazil.ORCID https://orcid.org/0000-0001-7506-308X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cariniana rubra, native to the Brazilian Cerrado and the Amazon-Cerrado ecotone, is traditionally used in folk medicine but remains underexplored. This study optimized extraction yield and bioactive compound content using ultrasound-assisted extraction (UAE) and Soxhlet extraction. A central composite rotational design (CCRD) assessed ethanol concentration and extraction time, with response surface modeling (RSM) determining optimal conditions. UAE yielded 49.60% (50% ethanol, 132 min) and Soxhlet 25.25% (78% ethanol, 300 min). Maximum phenolic compound contents were 382.62 mg GAE g

Indexed as

AntioxidantsPhenolsPlant ExtractsBiphenyl CompoundsBrazilFlavonoidsPicratesUltrasonic Waves1,1-diphenyl-2-picrylhydrazylAntioxidantsBiphenyl CompoundsFlavonoidsPhenolsPicratesPlant Extractsantioxidantsjequitibá‐vermelhophytochemistryresponse surface methodologytotal phenolic compounds

Identifiers

PMID40674638
PMCPMC12629157

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.