Evidence map›Paper›PMID 40674582›Full record

ArticleBioinformatics (Oxford, England)2025

Estimating sparse regression models in multi-task learning and transfer learning through adaptive penalisation.

Armin Rauschenberger, Petr V Nazarov, Enrico Glaab

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Armin RauschenbergerBioinformatics and Artificial Intelligence, Department of Medical Informatics, Luxembourg Institute of Health (LIH), 1445 Strassen, Luxembourg.ORCID 0000-0001-6498-4801
Petr V NazarovBioinformatics and Artificial Intelligence, Department of Medical Informatics, Luxembourg Institute of Health (LIH), 1445 Strassen, Luxembourg.ORCID 0000-0003-3443-0298
Enrico GlaabBiomedical Data Science, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362 Esch-sur-Alzette, Luxembourg.ORCID 0000-0003-3977-7469

Funding

Clinnova-Federating Digital Medicine in Europe ncer/23/16695277Luxembourg Institute of HealthLuxembourg National Research Fund
6 · The paper itself

Abstract

methodHere, we propose a simple two-stage procedure for sharing information between related high-dimensional prediction or classification problems. In both stages, we perform sparse regression separately for each problem. While this is done without prior information in the first stage, we use the coefficients from the first stage as prior information for the second stage. Specifically, we designed feature-specific and sign-specific adaptive weights to share information on feature selection, effect directions, and effect sizes between different problems.

resultsThe proposed approach is applicable to multi-task learning as well as transfer learning. It provides sparse models (i.e. with few non-zero coefficients for each problem) that are easy to interpret. We show by simulation and application that it tends to select fewer features while achieving a similar predictive performance as compared to available methods. AVAILABILITY AND IMPLEMENTATION: An implementation is available in the R package "sparselink" (https://github.com/rauschenberger/sparselink, https://cran.r-project.org/package=sparselink).

Indexed as

Computational BiologyMachine LearningAlgorithmsComputer SimulationRegression Analysis

Identifiers

PMID40674582
PMCPMC12502914

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.