Evidence map›Paper›PMID 40674315›Full record

ArticlePloS one2025

Association between depression and health care expenditure in middle-aged and older patients with heart disease.

Shushu You, Xiang Gu, Jing Sui, Ziyu Xiang, Fan Gao

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shushu YouSchool of Law and Public Affairs, Research Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing, China.ORCID https://orcid.org/0009-0008-5080-7159
Xiang GuInstitute of Public Safety Governance, School of Emergency Management, Nanjing University of Information Science & Technology, Nanjing, China.
Jing SuiSchool of Law and Public Affairs, Research Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing, China.
Ziyu XiangSchool of Law and Public Affairs, Research Institute for Environment and Health, Nanjing University of Information Science and Technology, Nanjing, China.
Fan GaoBusiness School of Hohai University, Hohai University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients with heart disease frequently experience a heightened incidence of depression, thereby affecting their overall medical expenditures. Nevertheless, earlier investigations have focused on the healthcare costs incurred by individual patients with heart disease or those with depression. The present study assessed the correlation between depression and the medical expenditures of patients with heart disease, highlighting the importance of mental health care for patients with with heart disease.

methodUsing data from Charles, we identified 2445 middle-aged and older patients with heart disease based on their completed medical expenditure-related questionnaires. The study further calculated the questionnaire data and used multiple linear regression analysis to control for demographic variables to evaluate the relationship between depressive symptoms and medical expenses.

resultsIn our sample, the presence or absence of depressive symptoms exhibited statistically significant differences (p < 0.05) in the medical expenditures of patients. Approximately 50.27% of heart disease patients had depressive symptoms. Depression level, gender, education level, type of health insurance, consumption level, and number of other chronic diseases were significantly associated with higher medical expenditures. A positive correlation was found between depressive symptoms and medical expenses.

conclusionHeart disease patients exhibiting depressive symptoms incurred higher medical expenditures compared to their counterparts without depression. The findings of this study imply the need to augment mental health care services for older individuals with heart disease and to enhance collaborative care interventions within the context of heart disease.

Indexed as

DepressionHealth ExpendituresHeart DiseasesAgedAged, 80 and overFemaleHumansMaleMiddle AgedSurveys and Questionnaires

Identifiers

PMID40674315
PMCPMC12270092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.