Evidence map›Paper›PMID 40673997›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2026

The social ambivalence and disease model: Childhood trauma as an antecedent factor linking spousal ambivalence to inflammation.

Bert N Uchino, Tracey Tacana, Joshua Landvatter, Brian W Baucom, Timothy W Smith, Samantha Joel, Christopher Fagundes

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Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Bert N UchinoDepartment of Psychology, University of Utah.ORCID 0000-0002-3036-6164
Tracey TacanaDepartment of Psychology, University of Utah.
Joshua LandvatterDepartment of Family and Preventive Medicine, University of Utah.
Brian W BaucomDepartment of Psychology, University of Utah.ORCID 0000-0002-0263-3763
Timothy W SmithDepartment of Psychology, University of Utah.
Samantha JoelDepartment of Psychology, University of Western Ontario.
Christopher FagundesDepartment of Psychology, Rice University.

Funding

Understanding Relationship Ambivalence and its Links to Cardiovascular HealthR01HL137606 · NHLBI · UNIVERSITY OF UTAH · PI UCHINO, BERT N. · 2018 to 2020
$1.1M
NHLBI NIH HHSNHLBI NIH HHS R01 HL137606
6 · The paper itself

Abstract

objectiveAmbivalence in relationships is related to health-relevant biological outcomes. However, the antecedent processes that contribute to this association are unknown. The primary aim of this study was to test the prediction of the social ambivalence and disease model, which highlights the potential role of childhood trauma as an antecedent factor linking spousal ambivalence to inflammation.

methodA sample of 107 heterosexual couples who had been married for at least 10 years was recruited. Participants completed the social relationship index to assess spousal ambivalence and the Childhood Trauma Questionnaire. Blood was drawn to determine levels of high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 as measures of inflammation.

resultsConsistent with the social ambivalence and disease model, there was a significant indirect effect in which childhood trauma was related to greater spousal ambivalence which in turn was associated with higher hs-CRP levels. No evidence for the statistical mediational model was found for interleukin-6.

conclusionsThese results highlight the potential role of childhood trauma as an antecedent factor linking spousal ambivalence to hs-CRP. It also highlights potential pathways that might be targeted for interventions pending further work. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

InflammationInterpersonal RelationsSpousesAdultC-Reactive ProteinFemaleHumansInterleukin-6MaleMiddle AgedC-Reactive ProteinIL6 protein, humanInterleukin-6

Identifiers

PMID40673997
PMCPMC12313190

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.