Evidence map›Paper›PMID 40673988›Full record

ArticleNeurosurgical review2025

One-year outcomes of the drug eluting stent in the treatment of severe vertebral artery ostium stenosis: single-center experience.

Yongkai Qin, Liyang Zhang, Junfei Han, Bo Li, Haitong Xu, Baorui Zhang, Yingchao Jing

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Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yongkai QinDepartment of Neurosurgery, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, 516002, Guangdong, China.
Liyang ZhangDepartment of Neurosurgery, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, 516002, Guangdong, China.
Junfei HanDepartment of Neurosurgery, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, 516002, Guangdong, China.
Bo LiDepartment of Neurosurgery, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, 516002, Guangdong, China.
Haitong XuDepartment of Neurosurgery, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, 516002, Guangdong, China.
Baorui ZhangDepartment of Neurosurgery, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China. 15210922626@163.com.
Yingchao JingDepartment of Neurosurgery, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, 516002, Guangdong, China. jingyingchao@126.com.

Funding

Beijing Natural Science Foundation 7244312
6 · The paper itself

Abstract

background and purposeThe Maurora stent (Drug eluting stent) is the first rapamycin-eluting vertebral artery stent system, and currently, there are no studies on the one-year outcomes of the Maurora stent in the treatment of severe vertebral artery ostium stenosis. Therefore, this study utilizes Cumulative sum (CUSUM) curve analysis to evaluate the one-year prognosis and restenosis rate of the Maurora stent in patients with severe stenosis at the vertebral artery origin.

methodsAll patients were arranged in chronological order according to the sequence of their surgeries. CUSUM analysis was employed to assess the surgical learning curve. The point at which the CUSUM learning curve begins to descend marks the number of cases required to achieve procedural proficiency; this point delineates the transition from the initial stable phase to the mature phase. Postoperative Modified Rankin Scale(mRS) and NIHSS scores are visualized using histograms.

resultsUltimately, 38 patients met the inclusion and exclusion criteria and were included in the analysis. At the 1-year follow-up, 89.47% of patients had an MRS score of 0, showing a statistically significant improvement compared to preoperative values (p < 0.05). The MRS scores at 1year post-procedure showed a statistically significant difference between the mature and stable groups (P < 0.05).

conclusionsThe study showed that the Maurora stent (Drug eluting stent) is safe and effective in treating severe vertebral artery ostium stenosis, offering significant clinical value.

Indexed as

Drug-Eluting StentsVertebral ArteryVertebrobasilar InsufficiencyAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSirolimusTreatment OutcomeSirolimusCUSUMMaurora stentmRSNIHSSSevere vertebral artery ostium stenosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.