Evidence map›Paper›PMID 40673954›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Splenial lesions of the corpus callosum: a comprehensive study on etiology, clinical presentation, radiological features, and prognostic insights.

Xiuming Gao, Yanan Wang, Min Zhang, Xiaona Shang, Miaomiao Sang, Tao Feng, Li Ma, Yi Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiuming Gao *The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, 213004, China.
Yanan Wang *Department of Rehabilitation Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China.
Min Zhang *Graduate School, Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China.
Xiaona Shang *Department of Rehabilitation Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China.
Miaomiao Sang *Department of Rehabilitation Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China.
Tao FengDepartment of Rehabilitation Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China.
Li MaDepartment of Rehabilitation Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China.
Yi ZhangThe Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, 213004, China. zhangyizhe1975@163.com.ORCID http://orcid.org/0000-0001-6251-3475

Funding

faculty-level projects of the Affiliated Hospital of Xuzhou Medical University 2020KB003faculty-level projects of the Affiliated Hospital of Xuzhou Medical University 2022ZL09faculty-level projects of the Affiliated Hospital of Xuzhou Medical University 2023ZL14General Projects of Philosophy and Social Sciences Research in Universities in 2020 2020SJA1069Key Project of Youth Science and Technology Innovation of Xuzhou Municipal Health Commission XWKYSL20210164Key Research and Development Program (Social Development) of Xuzhou Science and Technology Bureau KC22131
6 · The paper itself

Abstract

The corpus callosum (CC), situated at the base of the interhemispheric fissure, serves as the largest transverse commissural fiber bundle connecting the two hemispheres of the brain. The posterior segment of the CC is referred to as the "splenium". A spectrum of congenital and acquired pathologies can affect the splenium, presenting with a heterogeneous and multifaceted clinical phenotype. Affected individuals often exhibit signs of hemispheric dysfunction and manifestations indicative of interhemispheric disconnection. MRI is recognized for its superior sensitivity and anatomical resolution in the depiction of CC lesions. Therefore, this study presented a comprehensive review, organization, and analysis of diseases involving splenial lesions of the corpus callosum. We detailed the etiology, clinical presentation, MRI characteristics, and prognosis of these conditions, aiming to enhance the accuracy of diagnosis and inform the management of splenial CC lesions.

Indexed as

Brain DiseasesCorpus CallosumHumansMagnetic Resonance ImagingPrognosisClinical manifestationsCorpus callosumEtiologyPrognosisRadiology

Identifiers

PMID40673954

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.