Evidence map›Paper›PMID 40673812›Full record

ArticleBiomacromolecules2025

Thermally Cured Gelatin-Methacryloyl Hydrogels Form Mechanically Modulating Platforms for Cell Studies.

Sara Lipari, Andrea Marfoglia, Giovanni Sorrentino, Sophie Cazalbou, Ludovic Pilloux, Pasquale Sacco, Ivan Donati

Abstract read
In one paragraph

Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Next-Generation Hydrogels for Biliary Organoid Engineering.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara LipariDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 5, I-34127 Trieste, Italy.
Andrea MarfogliaCIRIMAT, Université de Toulouse, CNRS, Toulouse INP, 35 Chemin des Maraichers, 31062 Cedex 09 Toulouse, France.
Giovanni SorrentinoDepartment of Medical, Surgical and Health Sciences, University of Trieste, Strada di Fiume 477, 34139 Trieste, Italy.
Sophie CazalbouCIRIMAT, Université de Toulouse, CNRS, Toulouse INP, 35 Chemin des Maraichers, 31062 Cedex 09 Toulouse, France.
Ludovic PillouxLaboratoire de Génie Chimique, Université de Toulouse, CNRS, Toulouse INP, 35 Chemin des Maraichers, 31062 Cedex 09 Toulouse, France.
Pasquale SaccoDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 5, I-34127 Trieste, Italy.ORCID 0000-0002-4483-5099
Ivan DonatiDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 5, I-34127 Trieste, Italy.ORCID 0000-0003-3752-8346

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gelatin methacryloyl (GelMA) is a polypeptide derived from the methacryloylation of gelatin and retains the thermoresponsive behavior of gelatin. When cooled, GelMA undergoes a sol-gel transition. By photo-cross-linking GelMA in a heated ("Hot") or cooled ("Cold") state, it results in a set of hydrogels with distinct properties. To date, the mechanical properties of these resulting hydrogels have not been fully elucidated. Here, we show that "Cold" hydrogels are viscoelastic, while "Hot" hydrogels are almost completely elastic. These features have remarkable implications for cell-substrate interactions

Indexed as

GelatinHydrogelsMethacrylatesAnimalsCell AdhesionFibroblastsMiceTemperatureGelatingelatin methacryloylHydrogelsMethacrylates

Identifiers

PMID40673812
PMCPMC12344701

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.