Evidence map›Paper›PMID 40673773›Full record

ArticleMicrobial genomics2025

Natural variation of the streptococcal group A carbohydrate biosynthesis genes impacts host-pathogen interaction.

Kim Schipper, Sara M Tamminga, Nicholas Murner, Matthew Davies, Paul Berkhout, Debra E Bessen, Astrid Hendriks, Natalia Korotkova, Yvonne Pannekoek, Nina M van Sorge

Abstract read
In one paragraph

Article in Microbial genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kim SchipperDepartment of Medical Microbiology and Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Sara M TammingaDepartment of Medical Microbiology and Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Nicholas MurnerDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, KY, USA.
Matthew DaviesDepartment of Medical Microbiology and Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Paul BerkhoutDepartment of Medical Microbiology and Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Debra E BessenDepartment of Pathology, Microbiology, and Immunology, New York Medical College, Valhalla, NY, USA.
Astrid HendriksDepartment of Medical Microbiology and Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Natalia KorotkovaDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, KY, USA.
Yvonne PannekoekDepartment of Medical Microbiology and Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Nina M van SorgeDepartment of Medical Microbiology and Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.

Funding

Biogenesis and Function of Streptococcus Pyogenes Cell WallR01AI143690 · NIAID · UNIVERSITY OF KENTUCKY · PI KOROTKOVA, NATALIA · 2020 to 2024
$1.9M
Protective antibody in streptococcal infection modelsR01AI173565 · NIAID · NEW YORK MEDICAL COLLEGE · PI Debra E BESSEN · 2023 to 2026
$1.8M
Macrolide resistance transfer in Streptococcus pyogenesR21AI156226 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2021 to 2022
$461k
NIAID NIH HHS R01 AI143690NIAID NIH HHS R01 AI173565NIAID NIH HHS R21 AI156226Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Host-Pathogen InteractionsStreptococcus pyogenesAcetylglucosamineBacterial ProteinsCell WallGenetic VariationGenome, BacterialHumansMultigene FamilyStreptococcal InfectionsAcetylglucosamineBacterial Proteinsgroup A carbohydrategroup A Streptococcusgroup IIA-secreted phospholipasePubMLSTStreptococcus pyogenes

Identifiers

PMID40673773
PMCPMC12282279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.