Evidence map›Paper›PMID 40673681›Full record

ReviewVirulence2025

The function and mechanism of protein acylation in the regulation of viral infection.

Lei Song, Ziang Wei, Pan Shang, Shijie Hu, Lei Chen, Lili Niu, Yan Wang, Mailin Gan, Linyuan Shen, Li Zhu and 1 more

Abstract readReview
In one paragraph

Review in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lei SongFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Ziang WeiFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Pan ShangFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Shijie HuFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Lei ChenFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Lili NiuFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Yan WangFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Mailin GanFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Linyuan ShenFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Li ZhuFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.
Ye ZhaoFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (FAGREIKLSP), Sichuan Agricultural University, Chengdu, Sichuan, PR China.ORCID 0009-0004-3287-7883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein acylation modification is one of the most important protein post-translational modifications, which regulates the function of the protein by adding acyl groups to the residues of the protein. Protein acylation plays a crucial role in viral infection. Acylation can influence viral proteins, thereby regulating processes such as viral entry, replication, and assembly. Additionally, acylation regulates viral infection by regulating interferon pathway, cell metabolism, and signal transduction. This paper mainly elucidates the mechanism of acetylation, succinylation, and palmitoylation in the regulation of viral infection.

Indexed as

Protein Processing, Post-TranslationalViral ProteinsVirus DiseasesVirusesAcetylationAcylationAnimalsHost-Pathogen InteractionsHumansLipoylationSignal TransductionVirus InternalizationVirus ReplicationViral ProteinsacetylationAcylationpalmitoylationsuccinylationviral infection

Identifiers

PMID40673681
PMCPMC12279274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.