Evidence map›Paper›PMID 40673640›Full record

ArticlePest management science2025

Discovery of new PSII inhibitors: systematic investigation for herbicidal activity screening, properties, and mode of action.

Mirjalol Umurzokov, Danhee Kim, Jin-Seog Kim, Kwang Min Cho, Jung Sup Choi, Kee Woong Park, Hee Nam Lim

Abstract read
In one paragraph

Article in Pest management science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mirjalol Umurzokov *Daeseungbiofarm Co., Ltd., Daejeon, Republic of Korea.
Danhee Kim *Chemical Research Team, New Agrochemical Research Institute, Farmhannong, Nonsan-si, Republic of Korea.
Jin-Seog KimDaeseungbiofarm Co., Ltd., Daejeon, Republic of Korea.
Kwang Min ChoDaeseungbiofarm Co., Ltd., Daejeon, Republic of Korea.
Jung Sup ChoiEco-Friendly New Materials Research Center, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Kee Woong ParkDaeseungbiofarm Co., Ltd., Daejeon, Republic of Korea.
Hee Nam LimDepartment of Chemistry, Yeungnam University, Gyeongsan, Republic of Korea.ORCID https://orcid.org/0000-0002-0051-1578

Funding

National Research Foundation of Korea NRF-2019R1C1C1004970
6 · The paper itself

Abstract

backgroundThe research focused on developing effective photosystem II (PSII) inhibiting triazine-derived herbicidal compounds from the internal chemical library. Initially, the compounds were screened for their herbicidal activity using Spirodela polyrhiza (SPIPO) assays. Subsequently, compounds with stronger activity were synthesized on a gram scale and further investigated for their phytotoxicity, mobility, and mode of action.

resultsIn the SPIPO screenings, two compounds, K-31706 and K-31487, showed superior efficacy at concentrations exceeding 0.4 μm, surpassing the commonly used PSII inhibition herbicide, atrazine. Both compounds showed promising performance, especially in pre-emergence applications under greenhouse conditions, with the application rate causing 50% biomass reduction below 100 g a.i. ha

conclusionOverall, K-31706 and K-31487 are nonselective PSII inhibitors that block the electron transport in PSII, positioning them as potentially useful active ingredients for further investigation. © 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

AraceaeHerbicidesPhotosystem II Protein ComplexTriazinesDigitariaPlant WeedsHerbicidesPhotosystem II Protein ComplexTriazinescontact herbicideGR₅₀ valuesnonselectivePSII inhibitiontriazine derivatives

Identifiers

PMID40673640
PMCPMC12441759

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.