Evidence map›Paper›PMID 40673550›Full record

ArticleJournal of the American Heart Association2025

Prevalence, Characteristics, and Outcomes of Children With Congenital Heart Disease Undergoing Noncardiac Surgery in the Presence or Absence of COVID-19 Infection During the Pandemic.

David Faraoni, James A DiNardo, Viviane G Nasr

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David FaraoniDivision of Cardiac Anesthesia. Department of Anesthesiology, Critical Care, and Pain Medicine Boston Children's Hospital, Harvard Medical School Boston MA USA.ORCID 0000-0002-1093-4523
James A DiNardoDivision of Cardiac Anesthesia. Department of Anesthesiology, Critical Care, and Pain Medicine Boston Children's Hospital, Harvard Medical School Boston MA USA.
Viviane G NasrDivision of Cardiac Anesthesia. Department of Anesthesiology, Critical Care, and Pain Medicine Boston Children's Hospital, Harvard Medical School Boston MA USA.ORCID 0000-0002-2321-3987

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with congenital heart disease undergoing noncardiac surgery are at increased risk of perioperative complications. The objectives of our study are (1) to describe the prevalence and characteristics of children undergoing noncardiac surgery in the presence or absence of COVID-19 infection and (2) describe the association between preoperative diagnosis of COVID-19 and outcomes.

methodsWe identified all children who underwent surgery between 2017 and 2022 in the American College of Surgeons National Surgical Quality Improvement Program pediatric database. Starting in 2021, the presence of a preoperative diagnosis of COVID-19 was reported in the database. The outcomes included 30-day mortality and the incidence of the following major postoperative outcomes: cardiac arrest, reintubation, pneumonia, sepsis, and readmission. A composite end point that includes the presence of at least 1 of the abovementioned complications was created.

resultsWe identified 2919 patients with a preoperative diagnosis of COVID-19 versus 537 622 without. Patients with a preoperative diagnosis of COVID-19 underwent emergent procedures more often (64% versus 29%). Using multivariable logistic regression, the presence of preoperative diagnosis of COVID-19 increased the incidence of the composite endpoint (odds ratio [OR], 1.37 [95% CI, 1.19-1.56];

conclusionsOur study describes the prevalence and characteristics of children with congenital heart disease undergoing noncardiac surgery during the COVID-19 pandemic. We report that the preoperative diagnosis of COVID-19 and the presence of congenital heart disease significantly increased the risk of complications.

Indexed as

COVID-19Heart Defects, CongenitalPostoperative ComplicationsSurgical Procedures, OperativeAdolescentChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornMalePrevalenceRetrospective StudiesRisk Factorscongenital heart diseaseCOVID‐19 infectionnoncardiac surgeryoutcomes

Identifiers

PMID40673550
PMCPMC12449998

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.