ArticleJournal of the American Heart Association2025
When Is the Broken Heart Most Dangerous? Assessing Risk Factors to Predict Inpatient Death in Takotsubo Cardiomyopathy: Analysis of the National Inpatient Sample for 2021.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- A nomogram for predicting in-hospital death in a multinational cohort of patients with takotsubo syndrome.European journal of clinical investigation · 2026Article
- When a Woman's Heart Fails to Contain: Takotsubo Syndrome as a Gendered Collapse of Emotional Regulation.Life (Basel, Switzerland) · 2025Review
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14 authors.
Funding
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Abstract
backgroundTakotsubo cardiomyopathy (TC) has a similar clinical presentation to acute coronary syndromes (ACS). As the prevalence and influence on clinical decisions of this condition are being increasingly recognized, prognostic factors have yet to be established. We applied known near-term acute coronary syndrome mortality risk factors to determine their prognostic value in TC. This study aimed to assess the patient characteristics and comorbidities predicting inpatient death from TC. Understanding these risk factors is essential for clinical decision making and improving prognostic assessments.
methodsWe analyzed the National Inpatient Sample database for 2021. Inclusion criteria were principal diagnosis of TC (
resultsA total of 9109 admissions for TC were identified (10.3% men and 89.7% women) with a mean age of 67 years and an inpatient mortality rate of 2.31%. On univariate regression, age (odds ratio [OR], 1.04;
conclusionsPreexisting heart failure and a history of chronic kidney disease are poor prognostic factors in patients presenting with TC. Further large-scale studies are required to validate our findings.
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