Evidence map›Paper›PMID 40673501›Full record

ArticleJournal of the American Heart Association2025

Right Ventricular Function Score by Echocardiography for Predicting Outcomes After Heart Transplantation.

Wei Sun, Yuji Xie, Ye Zhu, Yun Yang, Xin Zhang, Nianguo Dong, Guohua Wang, Yuman Li, Jing Wang, Qing Lv and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wei SunDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Yuji XieDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.ORCID 0000-0002-5755-4819
Ye ZhuDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Yun YangDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.ORCID 0000-0001-6467-2656
Xin ZhangDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.ORCID 0000-0001-5468-6210
Nianguo DongDepartment of Cardiovascular Surgery Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Guohua WangDepartment of Cardiovascular Surgery Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.
Yuman LiDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.ORCID 0000-0002-4388-8199
Jing WangDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.ORCID 0000-0002-3773-1005
Qing LvDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.ORCID 0000-0002-4142-9474
Mingxing XieDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.ORCID 0000-0003-4984-1567
Li ZhangDepartment of Ultrasound Medicine Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China.ORCID 0000-0003-1620-1512

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impaired right ventricular (RV) function may occur after heart transplantation (HT). This study aimed to develop a straightforward RV function score (RVFS) using echocardiography to predict adverse clinical events in a large cohort of subjects after HT.

methodsA total of 357 consecutive patients post HT who underwent echocardiography at our single institution were retrospectively included. RV systolic function was evaluated by echocardiography. A multivariate Cox regression analysis was performed to identify the independent predictors of RV function for adverse clinical events.

resultsDuring a median follow-up of 39 months from the date of the echocardiography, a composite of adverse events that included death and major adverse cardiac events occurred in 51 patients. The multivariate Cox analysis revealed that RV fractional area change, tricuspid annular plane systolic excursion, and RV free wall longitudinal strain were independent predictors of outcomes after HT. The RVFS was constructed based on these 3 parameters, assigning a value of 1 when a predictor was below its cutoff value from receiver operating characteristic curves and 0 when above. The RVFS outperformed separate RV function parameters in predicting outcomes (area under the curves: 0.84 versus 0.64-0.78,

conclusionsThe RVFS, a readily obtainable echo score that combines multiple RV function parameters, exhibits incremental value and significant potential as a robust predictor for adverse outcomes in clinically stable patients after HT.

Indexed as

EchocardiographyHeart TransplantationHeart VentriclesVentricular Dysfunction, RightVentricular Function, RightAdultAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk FactorsROC CurveTime Factorsechocardiographyheart transplantationprognosisright ventricular function score

Identifiers

PMID40673501
PMCPMC12449958

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.