ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2026
A multidisciplinary Delphi consensus on the modern definition of pruritus: Sensation and disease.
Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review.International journal of dermatology · 2026Pooled it
- Effects of Psychological Interventions on Itch, Scratching, and Excoriations: A Systematic Review and Meta-analysis.Acta dermato-venereologica · 2026Pooled it
- European S2k Guideline on Chronic PruritusActa dermato-venereologica · 2025Guideline
- Immunopathogenesis of itch: an integrative framework for chronic pruritus.JID innovations : skin science from molecules to population health · 2026Review
- [How classification and guidelines simplify the care of pruritus patients. A guest commentary].Dermatologie (Heidelberg, Germany) · 2026Article
- Words matter: reclassifying chronic pruritus of unknown origin as neuroimmune pruritus.JAAD international · 2026Article
- A multidisciplinary Delphi consensus on the modern definition of pruritus: Sensation and disease.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Article
- Chronic Pruritus in Older Adults: Prevalence, Associations, and Pruritus-specific Quality of Life.Acta dermato-venereologica · 2025Article
- Development of the pruritus-associated stress scale: a cross-sectional pilot study.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundThe definition of pruritus (synonym: itch) dates back to the 17th century and does not address the complexity of the sensation or the nature of pruritus as a disease.
objectivesElaborate a new definition of pruritus comprising emotional aspects, stages and causal attributes.
methodsIn a pre-Delphi phase, stakeholders from pruritus-relevant global societies and patients elaborated itch definition proposals. In a Delphi phase, consensus was achieved when ≥75% of the voting participants agreed (7-9 Likert scale rating range) on a statement.
resultsIn two Delphi rounds, two statements defining the itch sensation and nine defining chronic pruritus as a disease achieved consensus. The definition of pruritus as an unpleasant sensation commonly triggering an urge to scratch mentions that external or internal factors can trigger, worsen, or improve pruritus. Chronic pruritus is described as a symptom of diseases but also as an independent disease. The definition of chronic pruritus includes temporal, physiological, causal, and quality of life aspects.
conclusionsThe new definition of pruritus allows the sensation to be separated from a disease state and aims to support practical use, including communication with patients, health authorities, and other stakeholders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.