Evidence map›Paper›PMID 40673466›Full record

ArticleJournal of paediatrics and child health2025

Methodology of the Updated and Expanded Australasian Bronchiolitis Guideline.

Kate Loveys, Emma J Tavender, Franz E Babl, Elizabeth Cotterell, Libby Haskell, Sharon O'Brien, Ed Oakley, Catherine Wilson, Meredith L Borland, Stuart R Dalziel and 1 more

Abstract read
In one paragraph

Article in Journal of paediatrics and child health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Australasian Bronchiolitis Guideline: 2025 Update.Journal of paediatrics and child health · 2025
    Guideline
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kate LoveysDepartment of Paediatrics: Child and Youth Health, School of Medicine, The University of Auckland, Auckland, New Zealand.ORCID 0000-0003-0694-4830
Emma J TavenderEmergency Research, Clinical Sciences, Murdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID 0000-0002-7230-712X
Franz E BablEmergency Research, Clinical Sciences, Murdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID 0000-0002-1107-2187
Elizabeth CotterellArmidale Rural Referral Hospital, Armidale, New South Wales, Australia.ORCID 0000-0001-8469-8394
Libby HaskellDepartment of Paediatrics: Child and Youth Health, School of Medicine, The University of Auckland, Auckland, New Zealand.ORCID 0000-0002-8706-3674
Sharon O'BrienEmergency Department, Perth Children's Hospital, Perth, Western Australia, Australia.ORCID 0000-0002-5980-4682
Ed OakleyDepartments of Paediatrics and Critical Care, The University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0002-3712-6200
Catherine WilsonEmergency Research, Clinical Sciences, Murdoch Children's Research Institute, Parkville, Victoria, Australia.ORCID 0000-0001-5893-4226
Meredith L BorlandEmergency Department, Perth Children's Hospital, Perth, Western Australia, Australia.ORCID 0000-0002-5326-5008
Stuart R DalzielDepartment of Paediatrics: Child and Youth Health, School of Medicine, The University of Auckland, Auckland, New Zealand.ORCID 0000-0003-0522-9579
Paediatric Research in Emergency Departments International Collaborative (PREDICT) Network

Funding

Cure KidsNational Health and Medical Research CouncilRoyal Children's Hospital FoundationState Government of Victoria
6 · The paper itself

Abstract

backgroundBronchiolitis is the most common reason for hospital admission in infants in Australia and Aotearoa New Zealand (AoNZ), with care historically affected by practice variation, including use of ineffective therapies. The Paediatric Research in Emergency Departments International Collaborative (PREDICT) developed the first Australasian (Australia, AoNZ) bronchiolitis guideline in 2016, providing evidence-based guidance on the management of infants (< 12 months of age), presenting or admitted to hospital with bronchiolitis. In 2022, PREDICT initiated a guideline update to include new evidence and expand the scope to include intensive care (up to intubation), management of SARS-CoV-2 co-infection, and respiratory syncytial virus prevention.

aimThis article outlines the methodology used in the guideline update, following AGREE and CheckUp reporting standards.

methodsA Guideline Advisory Group and Guideline Development Committee, consisting of 29 clinical and methodological experts from Australasia, developed the guideline with consumer input. Forty-one scoping questions on 25 topics were investigated. Systematic searches were performed by a subject librarian across five electronic databases (last search 24/01/24). Screening of 13,932 new articles occurred independently, in duplicate in two stages. The results of 431 articles were synthesized narratively and quantitatively where appropriate, per topic. Risk of bias was evaluated using appropriate tools. GRADE methodology was used to assess evidence quality and develop the recommendations, which were finalised through consensus voting across three guideline development meetings.

resultsThe update produced 41 recommendations (33 evidence-based, 8 consensus-based; including 11 new and 7 with key revisions), covering bronchiolitis investigations, management and RSV prevention. Interest-holder groups consulted on the recommendations.

conclusionThe Australasian Bronchiolitis Guideline was updated and expanded according to AGREE and CheckUp reporting standards.

Indexed as

BronchiolitisPractice Guidelines as TopicAustralasiaAustraliaCOVID-19HumansInfantInfant, NewbornNew Zealandbronchiolitisguideline methodologyinfantspaediatricrespiratory

Identifiers

PMID40673466
PMCPMC12397842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.