Evidence map›Paper›PMID 40673283›Full record

ArticleJournal of oral biology and craniofacial research

Efficacy of leukocyte-platelet rich fibrin (L-PRF) plug in accelerating the maxillary canine retraction in young adults: A split mouth randomized controlled trial.

A Iswariya, Ashok Kumar Jena, Manaswini Mangaraj, Jitendra Sharan, Gautom Kumar Saharia

Abstract read
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Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A IswariyaDepartment of Dentistry, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India.
Ashok Kumar JenaDepartment of Dentistry, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India.
Manaswini MangarajDepartment of Biochemistry, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India.
Jitendra SharanDepartment of Dentistry, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India.
Gautom Kumar SahariaDepartment of Biochemistry, All India Institute of Medical Sciences, Sijua, Bhubaneswar, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the effect of the L-PRF plug on the rate of maxillary canine retraction during the comprehensive orthodontic treatment. Materials and methods: The present split-mouth randomized controlled trial included 15 female patients (age range, 18-25 yrs) requiring all 1st premolars extraction for correction of their malocclusion. Right and left sides of the maxillary arch in each patient were randomly allocated to control and experimental sides. Simultaneous canine retraction was initiated immediately after the extraction of 1st premolars on the control side, and placement of L-PRF plugs on the experimental side 1st premolar extraction socket. The amount of canine retraction was evaluated from 3D models of the maxillary study models prepared immediately before (T Results: Of 15 enrolled, one participant lost during the follow-up. The data of fourteen maxillary arches (14 experimental and 14 control sides) were analyzed. During the first four weeks of observation, the experimental sides had more canine retraction of 0.25 mm (P = 0.001). The mean concentrations of IL-6 at mesial and distal aspects of experimental and control side canines were comparable (P > 0.05). There was a significant increase in IL-6 concentration in the distal compared to the mesial aspects of canine in experimental sides at T Conclusion: Although the application of L-PRF accelerated the maxillary canine retraction by 0.32 mm throughout the eight weeks, with most of the acceleration occurring in the first four weeks, but it was not clinically significant in decreasing the total duration of orthodontic treatment.

Identifiers

PMID40673283
PMCPMC12266370

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.