Evidence map›Paper›PMID 40673231›Full record

ReviewFrontiers in psychiatry2025

Exploring emerging psychopathological characteristics and challenges of novel depression subtypes: insights from the literature.

Stefania Chiappini, Gaia Sampogna, Antonio Ventriglio, Giulia Menculini, Valerio Ricci, Mauro Pettorruso, Umberto Volpe, Giovanni Martinotti

Abstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stefania ChiappiniDepartment of Psychiatry, UniCamillus International University of Medical Sciences, Rome, Italy.
Gaia SampognaDepartment of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.
Antonio VentriglioDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Giulia MenculiniSection of Psychiatry, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Valerio RicciSan Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy.
Mauro PettorrusoDepartment of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University, Chieti, Italy.
Umberto VolpeSection of Psychiatry, Department of Neurosciences/DIMSC, Università Politecnica Delle Marche, Ancona, Italy.
Giovanni MartinottiDepartment of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University, Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Depression is a widespread global health issue, significantly impacting all areas of life and is a leading cause of disability. Societal changes, including technological and cultural shifts, and the emergence of new psychoactive substances, have influenced how depression manifests, introducing new clinical dimensions and challenges in its understanding and treatment. Summary: This review summarizes from a psychopathological and clinical point of view the most important features related to novel depression subtypes, specifically: I) Early-onset depression; II) Depression and social disconnection; III) Depression and Alcohol/Substance Use Disorder; IV) Depression and Gender Dysphoria; V) Depression, stressful events, and other environmental factors. For each domain, the available research evidence is summarized, starting from theoretical contributions to the relevant psychopathological descriptors with special attention to issues relevant for the clinical practice. Key Messages: Overall, the phenomenology of depression is currently enriched by new symptomatology entities, including the dimensions of boredom, shame, fatigue, alexithymia, and emotional dysregulation. Those symptoms prevail in different novel subtypes of depression deserving in the clinical practice special attention and focused interventions.

Indexed as

clinical subtypesdepressiondigital depressiondual diagnosismodern-type-depressionpsychopathology

Identifiers

PMID40673231
PMCPMC12263598

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.