ArticleMaterials today. Bio2025
Hemoadhican-based self-leveling Janus patch for comprehensive prevention of postoperative adhesions.
Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Infection-targeted innovations in anastomotic leak management: endoscopic advances, antimicrobial biomaterials, and precision strategies.Annals of medicine · 2026Review
- A CD14-Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- An AIE-active polyvinyl alcohol/berberine/hemoadhican smart hydrogel for scarless wound healing with visual pH monitoring.Materials today. Bio · 2026Article
- Concrete Structure Inspired 3D-Printed Framework Mechanically Reinforced Zwitterionic Hydrogel for Efficient Postoperative Abdominal Adhesion Prevention.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postoperative anti-adhesion materials face significant challenges, including dislocation, the induction of nonspecific tissue adhesions, and secondary fibrinolytic disorders. In this study, we developed a self-leveling, transient, unilaterally bonded Janus patch (J-HD) based on hemoadhican (HD). This patch consists of three distinct functional layers: an anti-adhesion layer, a reinforcement layer, and a wet tissue adhesion layer. Each layer serves a specific purpose: the bottom anti-adhesion layer, composed of HD and Pluronic F127 (PF127), effectively prevents cells, proteins, and tissues from adhering; the middle polyvinyl alcohol (PVA) reinforcement layer enhances the mechanical properties of the film, exhibiting a tensile strength of approximately 2.02 MPa; and the top HD adhesion layer provides strong adhesion to wet tissue with an interfacial toughness of approximately 223.85 J/m
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Registered trials
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