Evidence map›Paper›PMID 40673128›Full record

ArticleMaterials today. Bio2025

Red-emissive carbon dot-cobalt oxyhydroxide nanosystem: A turn-on sensor for α-Glucosidase activity and inhibitor identification.

Huihui Sun, Chuanyuan Gao, Yumin Yang, Changqing Liu, Han Qin, Mengyuan Tan, Jin Li, Xiaoxia Li, Kunze Du, Yanxu Chang

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huihui SunState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Chuanyuan GaoState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Yumin YangSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
Changqing LiuState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Han QinState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Mengyuan TanState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Jin LiState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Xiaoxia LiState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Kunze DuState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Yanxu ChangState Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of efficient methods for sensing αlpha-glucosidase (α-Glu) and screening its inhibitors has attracted significant attention due to their pivotal role in discovering therapeutic medicines for Type 2 diabetes. Herein, a low-cost and sensitive fluorometric strategy based on red carbon dots (R-CDs) and cobalt oxyhydroxide nanosheets (CoOOH NSs) had been established to detect α-Glu and screen its inhibitory compounds in natural products. As a switched fluorescence source, the fluorescence of R-CDs at 625 nm could be quenched by CoOOH NSs via Förster resonance energy transfer (FRET), assembled into nonfluorescent R-CDs@CoOOH nanocompositecomposites (R-CDs@CoOOH NCs). α-Glu hydrolyzed L-ascorbic acid-2-

Indexed as

Förster resonance energy transferInhibitorsPolygonum cuspidatumR-CDs@CoOOH NCsType 2 diabetesα-Glucosidase

Identifiers

PMID40673128
PMCPMC12264606

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.