Evidence map›Paper›PMID 40673063›Full record

ReviewBreathe (Sheffield, England)2025

Mediastinal staging of nonsmall cell lung cancer: what's new?

Claire Bradley, Nuria Novoa, Laura Riva, Sophia Lampaki, Sara Ricciardi, Michael Rovanias, Malek Chaabouni, Richard Turner, Antonia Zachariou, Georgia Hardavella and 1 more

Abstract readReview
In one paragraph

Review in Breathe (Sheffield, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Interventional pulmonology.Breathe (Sheffield, England) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Claire BradleyBelfast City Hospital Health and Social Services Trust, Respiratory Medicine, Belfast, UK.ORCID https://orcid.org/0000-0001-9184-103X
Nuria NovoaPuerta de Hierro University Hospital of Majadahonda, Madrid, Spain.
Laura RivaOncology Hospital Armando Businco, Department of Thoracic Surgery, Cagliari, Italy.
Sophia LampakiAristotle University of Thessaloniki, Respiratory Medicine, Thessalonike, Kentrike Makedonia, Greece.
Sara RicciardiSan Camillo Forlanini Hospital, Division of Thoracic Surgery, Department of Surgical, Medical, Molecular, Pathology and Critical Care, Rome, Italy.ORCID https://orcid.org/0000-0002-4638-8528
Michael RovaniasCare Medical Institure, Nicosia, Cyprus.
Malek ChaabouniAsklepios Kliniken Hamburg GmbH, Department of Pulmonology and Thoracic Oncology, Hamburg, Germany.
Richard TurnerPrincess Alexandra Hospital, Department of Respiratory, Sleep and Mycobacterial Medicine, Woolloongabba, Australia.ORCID https://orcid.org/0000-0002-3024-6971
Antonia ZachariouSotiria General Hospital of Chest Diseases of Athens, Respiratory Medicine Athens, Attica, Greece.
Georgia HardavellaSotiria General Hospital of Chest Diseases of Athens, 6th Department of Respiratory Medicine, Athens, Greece.
Neal NavaniUniversity College London, Medicine, London, UK.ORCID https://orcid.org/0000-0002-6412-7516

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, we explore the importance of accurate mediastinal staging in nonsmall cell lung cancer, which directly impacts management options and prognosis. We outline the various means of staging, including radiological and interventional techniques, with a focus on the advantages and limitations of the different approaches. The review also identifies ways in which mediastinal staging has changed over time, particularly with the advent of effective endoscopic nodal sampling, and how emerging research and developments may lead to further adjustments in clinical practice. The role of multidisciplinary decision making, particularly in complex cases, remains integral to the process of mediastinal staging in lung cancer.

Identifiers

PMID40673063
PMCPMC12260911

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.