Evidence map›Paper›PMID 40672873›Full record

ArticleFrontiers in neuroscience2025

A multi-graph convolutional network method for Alzheimer's disease diagnosis based on multi-frequency EEG data with dual-mode connectivity.

Qingjie Xu, Libing An, Haiqiang Yang, Keum-Shik Hong

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qingjie XuSchool of Automation, Institute for Future, Qingdao University, Qingdao, China.
Libing AnSchool of Pharmacy, Taishan Vocational College of Nursing, Taian, China.
Haiqiang YangSchool of Automation, Institute for Future, Qingdao University, Qingdao, China.
Keum-Shik HongSchool of Automation, Institute for Future, Qingdao University, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Alzheimer's disease (AD) is mainly identified by cognitive function deterioration. Diagnosing AD at early stages poses significant challenges for both researchers and healthcare professionals due to the subtle nature of early brain changes. Currently, electroencephalography (EEG) is widely used in the study of neurodegenerative diseases. However, most existing research relies solely on functional connectivity methods to infer inter-regional brain connectivity, overlooking the importance of spatial connections. Moreover, many existing approaches fail to fully integrate multi-frequency EEG features, limiting the comprehensive understanding of dynamic brain activity across different frequency bands. This study aims to address these limitations by developing a novel graph-based deep learning model that fully utilizes both functional and structural information from multi-frequency EEG data. Methods: This paper introduces a Multi-Frequency EEG data-based Multi-Graph Convolutional Network (MF-MGCN) model for AD diagnosis. This method integrates both functional and structural connectivity to more thoroughly capture the relationships among brain regions. By extracting differential entropy (DE) features from five distinct frequency bands of EEG signals for each segment and using graph convolutional networks (GCNs) to aggregate these features, the model effectively distinguishes between AD and healthy controls (HC). Results: The outcomes show that the developed model outperforms existing methods, achieving 96.15% accuracy and 98.74% AUC in AD and HC classification. Conclusion: These findings highlight the potential of the MF-MGCN model as a clinical tool for Alzheimer's disease diagnosis. This approach could help clinicians detect Alzheimer's at earlier stages, enabling timely intervention and personalized treatment plans.

Indexed as

Alzheimer’s disease diagnosisdual-mode connectivityEEGmulti-frequency analysismulti-graph convolutional network

Identifiers

PMID40672873
PMCPMC12263931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.