Evidence map›Paper›PMID 40672871›Full record

ArticleFrontiers in neuroscience2025

Assessment of flight fatigue using heart rate variability and machine learning approaches.

Dalong Guo, Cong Wang, Yufei Qin, Lamei Shang, Aijing Gao, Baosen Tan, Yubin Zhou, Guangyun Wang

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dalong GuoAir Force Medical Center, Air Force Medical University, Beijing, China.
Cong WangAir Force Medical Center, Air Force Medical University, Beijing, China.
Yufei QinAir Force Medical Center, Air Force Medical University, Beijing, China.
Lamei ShangAir Force Medical Center, Air Force Medical University, Beijing, China.
Aijing GaoAir Force Medical Center, Air Force Medical University, Beijing, China.
Baosen TanAir Force Medical Center, Air Force Medical University, Beijing, China.
Yubin ZhouAir Force Medical Center, Air Force Medical University, Beijing, China.
Guangyun WangAir Force Medical Center, Air Force Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accurate identification of flight fatigue is crucial for managing pilot training intensity and preventing aviation accidents. However, as a subjective perception, flight fatigue is often difficult to evaluate objectively. Heart rate variability (HRV), derived from electrocardiogram signals and regulated by the autonomic nervous system, is recognized as an effective biomarker for assessing fatigue status. This study proposes a novel HRV-based method for the automatic and objective classification of flight fatigue. This study involved an experimental investigation conducted with a cohort of 90 pilots. First, we conducted statistical analyses to investigate whether HRV features and respiratory rate indicators significantly differed across various fatigue levels. A subset of HRV features and the respiratory metric were used as input variables for four machine learning algorithms: decision tree, support vector machine, K-nearest neighbor, and light gradient-boosting machine (LightGBM). These models were applied to perform a three-level classification of flight fatigue. Finally, classification performance was evaluated using average accuracy, precision, recall, and F1 score. Among these models, LightGBM demonstrated the best performance, achieving an accuracy of 0.886 ± 0.057, precision of 0.837 ± 0.064, recall of 0.861 ± 0.086, and F1 score of 0.849 ± 0.067. These findings indicate that a LightGBM model trained on 12 selected HRV features and one respiratory indicator can accurately categorize flight fatigue into three levels. Fatigue can be detected even when mild, enabling real-time monitoring and early warning of flight fatigue. This approach holds potential for reducing fatigue-related flight accidents.

Indexed as

electrocardiogramflight fatigueheart rate variabilitylight gradient-boosting machinemachine learning

Identifiers

PMID40672871
PMCPMC12263958

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.