ArticleFrontiers in medicine2025
The change of retinal microvascular in APAC eyes and fellow PACS eyes detected using wide-field swept-source optical coherence tomographic angiography.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Long-term optic nerve head microvascular impairment after acute primary angle closure: an OCTA study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
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6 authors.
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Abstract
Purpose: This study aimed to quantitatively evaluate changes in vascular parameters in a 12 mm × 12 mm region centered on the fovea with wide-field swept-source optical coherence tomographic angiography (WF SS-OCTA), and establish their correlations with structural parameters in acute primary angle closure (APAC) eyes, as well as in fellow primary angle-closure suspect (PACS) eyes. Methods: In this retrospective study, WF SS-OCTA was utilized to measure vascular parameters in a 12 mm × 12 mm region centered on the fovea in 31 patients (31 APAC eyes and 31 fellow PACS eyes). Vascular parameters included vessel density (VD) of the superficial vascular complex (SVC) and deep vascular complex (DVC). Structural parameters comprised macular ganglion cell complex (GCC) thickness and peripapillary retinal nerve fiber layer (pRNFL) thickness. Pre- and postoperative (3 month after APAC attack) differences between APAC and PACS eyes were statistically analyzed. Results: No significant differences were observed in vascular density or structural parameters in PACS eyes pre- and postoperatively ( Conclusion: Wide-field SS-OCTA revealed spatially distinct vascular responses in APAC eyes: underlying axonal loss with concomitant SVC compromise in the 6-12 mm annular region centered on the fovea and partial DVC recovery at 3 months after APAC attack, highlighting WF SS-OCTA's utility in monitoring APAC progression.
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