ArticleFrontiers in oncology2025
Efficacy of opioid-free anesthesia in short-term recovery following laparoscopic-assisted colorectal tumor resection: a randomized trial.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Opioid-free anesthesia in enhanced recovery after surgery for gastrointestinal surgery: current status, challenges, and prospects.Frontiers in pharmacology · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to evaluate whether opioid-free anesthesia is non-inferior to opioid-based anesthesia in terms of short-term recovery quality in patients undergoing laparoscopic-assisted colorectal tumor resection. Methods: A randomized controlled trial was conducted with 102 participants, who were randomly assigned to one of two groups: opioid-free general anesthesia with thoracic epidural anesthesia (OFA) group and opioid-based general anesthesia with compound transversalis fascia nerve block (OA) group. The primary observation outcomes were the preoperative and postoperative Quality of Recovery-40 (QoR-40) questionnaire scores. Results: No statistically significant differences were observed in preoperative or postoperative QoR-40 scores between the two groups ( Conclusion: Opioid-free general anesthesia is not superior to opioid-based general anesthesia with transversalis fascia nerve block in terms of short-term postoperative recovery quality following laparoscopic-assisted colorectal tumor resection. Clinical Trial Registration: https://www.chictr.org.cn/, identifier 2023-12-08.
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