Evidence map›Paper›PMID 40672723›Full record

ReviewPostepy dermatologii i alergologii2025

The influence of immune system-related genes on the development of atopic dermatitis.

Dominika Cieśla, Tomasz Nowak

Abstract readReview
In one paragraph

Review in Postepy dermatologii i alergologii, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dominika CieślaDistrict Hospital in Zawiercie, Children's Clinic, Zawiercie, Poland.
Tomasz NowakDepartment of Biochemistry and Medical Genetics, School of Health, Medical University of Silesia, Katowice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a disease with a complex genetic background, in which only the predisposition to atopy is inherited. Genetic, environmental, and psychosomatic factors contribute to the development of this allergic inflammatory disease. The patient's age and population affiliation also play a significant role. Gene groups associated with AD are primarily: genes responsible for the epidermal barrier, interaction with the environment and related to the immune response. In turn, polymorphisms in these genes can affect the severity of atopic dermatitis through mechanisms such as excessive stimulation of the immune system or increased synthesis of immunoglobulin E (IgE). Among the genes related to the immune system that play an important role in the development of atopic dermatitis, we can distinguish: Chitinase-3-like protein 1 (

Indexed as

atopic dermatitisCHI3L1cytokineFcεRITLRs

Identifiers

PMID40672723
PMCPMC12262038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.