ReviewPostepy dermatologii i alergologii2025
Serofast state after syphilis treatment: implications and recommendations for clinical practice. Narrative review.
Review in Postepy dermatologii i alergologii, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Syphilis Co-Infection Among People Living with HIV in Romania: Epidemiological and Clinical Characteristics in a Single-Center Retrospective Study.Pathogens (Basel, Switzerland) · 2026Article
- Updates on epidemiology and diagnostic tests of syphilis in South Korea.The Korean journal of internal medicine · 2026Review
- Cytotoxic T-cell deficiency and sustained B-cell activation in serofast syphilis: a prospective observational study.Frontiers in immunology · 2026Observational
- A Case of Neuro- and Otosyphilis Successfully Managed with a Sequential Regimen Including Ceftriaxone.Infection and drug resistance · 2026Article
- Analysis of influencing factors for syphilis serofast and development and evaluation of a predictive model.Frontiers in immunology · 2026Article
- Divergent trends of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), syphilis, and gonorrhea in China: a national age-period-cohort analysis, 2006-2020.Frontiers in public health · 2025Article
- NELL1-Associated Membranous Nephropathy in a Patient with Papillary Thyroid Carcinoma: A Case Report and Literature Review.Glomerular diseasesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Serofast state is defined as an insufficient decrease in the non-treponemal reaction titre after 6-12 months for early syphilis or after 12-24 months for late syphilis counting from the recommended treatment, with the simultaneous resolution of the infection symptoms. Aim: The aim of this article was to review the current understanding of the serofast state. Additionally, data on recommended diagnostic and therapeutic approaches for patients with serofast state were presented. Methods: In order to review the current understanding in the field of serofast syphilis, the PubMed database was searched. Results: The available literature relating to serofast syphilis is mainly concerned with predictive factors of the serofast state. Conclusions: Understanding the predictive factors of the serofast state and its pathomechanism is crucial. This knowledge enables early identification of patients who, following treatment, may require increased clinical supervision and a slightly altered therapeutic management plan.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.