ArticleAmerican journal of translational research2025
Effect of interleukin-6 and interleukin-8 levels on pathogenic bacteria types in patients with advanced lung cancer and pulmonary infection during chemotherapy.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Observational
- Incidence and risk factors of infections in lung cancer patients receiving immunotherapy combined with chemotherapy: a real-world retrospective study.American journal of cancer research · 2026Article
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4 authors.
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Abstract
objectiveTo investigate the levels of interleukin-6 (IL-6) and interleukin-8 (IL-8) in patients with advanced lung cancer complicated by pulmonary infection during chemotherapy and their effects on the type of pathogenic bacteria.
methodWe retrospectively analyzed the clinical data of 196 patients from Wuhan Hankou Hospital (January 2021-June 2024). The incidence of pulmonary infection was assessed, and the levels of IL-6 and IL-8 were compared across different infection severities and pathogenic bacteria types. Spearman correlation analysis was used to determine associations, and logistic regression was performed to identify factors influencing different pathogenic bacteria infections.
resultThe lung infection rate was 24.49% (48/196). Pathogenic bacteria included 36 strains (64.29%) of Gram-negative bacteria (G
conclusionIn patients with advanced-stage lung cancer undergoing chemotherapy, elevated IL-6 and IL-8 levels were closely associated with pulmonary infection severity. Detection of these cytokines may help differentiate the types of pathogenic bacteria causing lung infections.
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