ArticleAmerican journal of translational research2025
Intrauterine adhesion after missed miscarriage evacuation: efficacy of different estrogen doses on incidence and risk factors.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the efficacy of different doses of estradiol valerate in preventing intrauterine adhesion (IUA) incidence and promoting endometrial recovery after curettage for retained abortion.
methodsA total of 188 patients who underwent Missed Miscarriage (MM) by curettage were retrospectively assigned to three groups based on the preoperative estradiol valerate dosage: Group A (3 mg/day), Group B (5 mg/day), and Group C (no estrogen). Postoperative outcomes, including IUA incidence (assessed by hysteroscopy), endometrial thickness (transvaginal ultrasound), menstrual recovery, and adverse reactions, were compared among groups. Logistic regression and ROC curve analysis were used to identify independent risk factors for IUA.
resultsGroup B showed the lowest IUA incidence (4.84% vs. 7.14% in Group A and 21.43% in Group C, P < 0.001), greater endometrium thickness at 14 days postoperatively, and shorter menstrual recovery time (P < 0.001). Preoperative endometrial thickness < 4 mm and a history of IUA were identified as independent risk factors (AUC = 0.760). The incidence of adverse reactions did not differ significantly among the groups (P > 0.05).
conclusionPreoperative administration of 5 mg/day estradiol valerate significantly reduces IUA incidence and enhances endometrial recovery after curettage. A thin endometrium and prior IUA history are key risk factors for postoperative adhesion formation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.