Evidence map›Paper›PMID 40672576›Full record

ArticleAmerican journal of translational research2025

Correlation between the severity of lumbar spinal stenosis and lumbar paraspinal muscle atrophy.

Xiaoyu Mu, Chongyu Zhao, Zhitao Shan, Li Deng, Xiaowei Zhou, Li Li

Abstract read
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Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiaoyu MuDepartment of Orthopedics and Traumatology, Kunming Municipal Hospital of Traditional Chinese Medicine (The Third Affiliated Hospital of Yunnan University of Chinese Medicine) Kunming 650000, Yunnan, China.
Chongyu ZhaoDepartment of Orthopedics and Traumatology, Kunming Municipal Hospital of Traditional Chinese Medicine (The Third Affiliated Hospital of Yunnan University of Chinese Medicine) Kunming 650000, Yunnan, China.
Zhitao ShanHeilongjiang University of Chinese Medicine Harbin 150000, Heilongjiang, China.
Li DengDepartment of Orthopedics and Traumatology, Kunming Municipal Hospital of Traditional Chinese Medicine (The Third Affiliated Hospital of Yunnan University of Chinese Medicine) Kunming 650000, Yunnan, China.
Xiaowei ZhouDepartment of General Practice, Kunming Municipal Hospital of Traditional Chinese Medicine (The Third Affiliated Hospital of Yunnan University of Chinese Medicine) Kunming 650000, Yunnan, China.
Li LiDepartment of Orthopedics and Traumatology, Kunming Municipal Hospital of Traditional Chinese Medicine (The Third Affiliated Hospital of Yunnan University of Chinese Medicine) Kunming 650000, Yunnan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the correlation between the severity of lumbar spinal stenosis (LSS) and the atrophy of lumbar paraspinal muscles.

methodsA retrospective analysis was conducted on 200 patients with LSS (stenosis group) and 60 individuals without lumbar spine disease (control group) treated at the Department of Orthopedics, Kunming Traditional Chinese Medicine Hospital, from January 2022 to October 2024. Using a 1.5T MRI system, we measured the total cross-sectional area (TCSA) and total fat-free cross-sectional area (TFCSA) of the multifidus, erector spinae, and psoas major muscles. Muscle atrophy was evaluated using the TFCSA/TCSA ratio, and its correlation with LSS severity was analyzed.

resultsThe stenosis group showed significantly lower TFCSA/TCSA ratios in the multifidus, erector spinae, and psoas major compared to controls (P<0.05). LSS severity was negatively correlated with the TFCSA/TCSA ratios of the multifidus (r=-0.504, P<0.05) and erector spinae (r=-0.562, P<0.05), but not with the psoas major (P>0.05). Similarly, the number of stenotic segments was negatively correlated with multifidus (r=-0.381) and erector spinae (r=-0.420) atrophy (P<0.05). TFCSA/TCSA ratios were significantly lower on the symptomatic side for all three muscles (all P<0.05).

conclusionThe severity and extent of LSS are significantly associated with atrophy of the multifidus and erector spinae, but not the psoas major. Greater muscle atrophy corresponds to a higher number of stenotic segments.

Indexed as

correlationLumbar spinal stenosismuscle atrophyparaspinal muscles

Identifiers

PMID40672576
PMCPMC12261186

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