SynthesisFrontiers in neurology2025
The effect of different exercise training modes on improving quality of life in patients with Parkinson's disease: a network analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07264114 (The Effect of Aquatic High-Intensity Interval Training on Balance, Physical Function, and Sarcopenia in Patients With Parkinson's Disease), which is not on this map. Cited by 3 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Aquatic High-Intensity Interval Training on Balance, Physical Function, and Sarcopenia in Patients With Parkinson's Disease: A Randomized Controlled Trial Protocol
Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Does Resistance Training Improve the Quality of Life of People With Parkinson's Disease? Evidence and Recommendations for Clinical Application Through a Systematic Review and Meta-Analysis of Randomized Clinical Trials.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Pooled it
- Exercise as a potent antidepressant intervention in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials.Frontiers in psychology · 2026Pooled it
- The effects of neuromuscular electrical stimulation on neurological function, balance, and quality of life in patients with parkinson's disease.Irish journal of medical science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Reduced quality of life is a typical manifestation of Parkinson's disease (PD) patients, and exercise has a significant effect on improving the quality of life of PD patients. However, it is still unclear which exercise is effective in improving quality of life for people with Parkinson's disease. The aim of this study was to compare effective exercises for improving quality of life in patients with Parkinson's disease through a network meta-analysis. Method: We conducted comprehensive database searches, including PubMed, Cochrane Library, Embase, Web of Science and CNKI. The included studies assessed methodological quality using the Cochrane Bias risk tool, and we collected information from the studies to compare the effects of 25 exercise interventions on quality of life in PD patients. Results: The results of the network meta-analysis showed that QG is higher than OE (MD, -9.26; 95%CI, -18.25 to -0.27), FAE (MD, -10.77; 95%CI -19.52 to -2.02), VR (MD, -10.65; 95%CI -19.70 to -1.60), TC (MD, -11.06; 95%CI -21.32 to -0.81), CT (MD, -11.42; 95%CI -20.73 to -2.11), RT (MD, -11.60; 95%CI -20.72 to -2.49), CE (MD -12.50; 95%CI -24.47 to -0.52), GT (MD -13.10; 95%CI -24.67 to -1.52) to better improve quality of life in patients with PD. DE is superior to TR (SMD, -2.10; 95%CI -3.75 to -0.45), BT (SMD, -2.63; 95%CI -4.93 to -0.32), BDJ (SMD, -4.14; 95%CI -6.15 to -2.14), RT (SMD, -4.54; 95%CI -6.94 to -2.14), TC (SMD, -5.28; 95%CI -7.73 to -2.84) in reduce depression. ROT is superior to TR (MD, 6.17; 95%CI 0.57 to 11.77), in improving balance capacity. Conclusion: Our study found that QG improved the quality of life in patients with PD better than other forms of exercise. DE is more effective than other exercises in reducing depression in PD patients. ROT is better at improving the balance of PD patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.