Evidence map›Paper›PMID 40672443›Full record

ArticleFrontiers in surgery2025

White blood cells, monocytes and thrombin time in predicting symptomatic hydrocephalus in patients with aneurysmal subarachnoid hemorrhage.

Hui Deng, Hongjuan Yang, Ruoyu Chen, Wei Xing, Jia Shi

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Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Hui Deng *Department of Neurosurgery, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Hongjuan Yang *Department of Endocrinology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Ruoyu Chen *Department of Neurosurgery, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Wei XingDepartment of Imaging, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Jia ShiDepartment of Neurosurgery, The Third Affiliated Hospital of Soochow University, Changzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the value of admission blood routine and coagulation function parameters in predicting acute symptomatic hydrocephalus in patients with aneurysmal subarachnoid hemorrhage (aSAH). Methods: This retrospective study included 423 patients with aSAH admitted to the Department of Neurosurgery of the Third Affiliated Hospital of Soochow University from November 2013 to September 2020. Demographic, clinical and laboratory data were collected. The patients were divided into hydrocephalus group ( Results: Among the 423 aSAH patients, 96 (22.70%) developed acute symptomatic hydrocephalus. Multivariate logistic regression analysis showed that, after adjusting for confounding factors, white blood cells (WBC) (OR = 1.121, 95% CI = 1.067-1.181), monocytes (M) (OR = 2.812, 95% CI = 1.183-6.699), and thrombin time (TT) (OR = 0.843, 95% CI = 0.729-0.948) were independently associated with the development of hydrocephalus. Further analysis of the area under the receiver operating characteristic (ROC) curve indicated that, compared to basic clinical data, the combined prediction model of "basic clinical data + WBC + M + TT" performed better (AUC = 0.728, 95% CI = 0.682-0.769, Conclusions: The WBC, M and TT within 24 h of admission in aSAH patients can be used to predict the occurrence of acute symptomatic hydrocephalus.

Indexed as

acute symptomatic hydrocephalusaneurysmal subarachnoid hemorrhagemonocytesthrombin timewhite blood cells

Identifiers

PMID40672443
PMCPMC12263645

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