Evidence map›Paper›PMID 40672435›Full record

ArticleTetrahedron letters2025

Catalytic Reductive Annulation Reactions of Alkenes Using Dihaloalkanes.

Sayan Roy, Divya Garg, Christopher Uyeda

Abstract read
In one paragraph

Article in Tetrahedron letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sayan RoyDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.
Divya GargDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.
Christopher UyedaDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.

Funding

Transition Metal Catalyzed Reductive Carbene Transfer ReactionsR35GM124791 · NIGMS · PURDUE UNIVERSITY · PI Christopher Uyeda · 2017 to 2026
$4.2M
NIGMS NIH HHS R35 GM124791
6 · The paper itself

Abstract

A nickel catalyst promotes the reductive annulation of alkenes using 1,3-dihalopropanes to provide substituted cyclopentanes. Mechanistic studies indicate that activation of the dihaloalkane occurs by a halogen-atom abstraction mechanism to generate a carbon-centered radical. Overall, the method provides direct access to saturated ring-systems from simple acyclic reaction partners.

Identifiers

PMID40672435
PMCPMC12263114

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.