Evidence map›Paper›PMID 40672430›Full record

ArticleAcute medicine & surgery

Fulminant myocarditis in immune-mediated thrombotic thrombocytopenic purpura: A case report.

Haruka Ishikita, Akira Endo, Keisuke Suzuki, Tomohiro Akutsu, Yuichi Araki, Koji Morishita

Abstract read
In one paragraph

Article in Acute medicine & surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haruka IshikitaDepartment of Acute Critical Care Medicine Tsuchiura Kyodo General Hospital Tsuchiura Japan.ORCID https://orcid.org/0009-0004-8773-1283
Akira EndoDepartment of Acute Critical Care Medicine Tsuchiura Kyodo General Hospital Tsuchiura Japan.
Keisuke SuzukiDepartment of Acute Critical Care Medicine Tsuchiura Kyodo General Hospital Tsuchiura Japan.
Tomohiro AkutsuDepartment of Acute Critical Care Medicine Tsuchiura Kyodo General Hospital Tsuchiura Japan.ORCID https://orcid.org/0000-0001-7132-3753
Yuichi ArakiDepartment of Acute Critical Care Medicine Tsuchiura Kyodo General Hospital Tsuchiura Japan.
Koji MorishitaDepartment of Acute Critical Care and Disaster Medicine Institute of Science Tokyo Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Thrombotic thrombocytopenic purpura is a life-threatening thrombotic microangiopathy characterized by systemic microvascular thrombosis. Cardiovascular complications, including myocardial ischemia and necrosis, are a leading cause of acute mortality. Case Presentation: A 54-year-old man was diagnosed with immune-mediated thrombotic thrombocytopenic purpura. On Day 2, he developed sudden cardiac arrest, requiring venoarterial extracorporeal membrane oxygenation for circulatory support. Echocardiography revealed diffuse severe hypokinesis, ventricular hypertrophy, and pericardial effusion. Myocardial biopsy performed on Day 3 showed no findings of microthrombi or necrosis. These findings suggested fulminant myocarditis rather than myocardial ischemia. The patient was successfully treated with multidisciplinary treatment including plasma exchange, achieving full recovery by Day 44. Conclusion: This case highlights fulminant myocarditis as a complication of immune-mediated thrombotic thrombocytopenic purpura. As myocarditis is potentially reversible, providing appropriate supportive therapy may contribute to an improved prognosis.

Indexed as

extracorporeal membrane oxygenationheart arrestpericardial effusionthrombotic microangiopathiesthrombotic thrombocytopenic purpura

Identifiers

PMID40672430
PMCPMC12266088

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.