ArticleFrontiers in nutrition2025
Non-linear association between dietary fiber intake and cognitive function mediated by vitamin E: a cross-sectional study in older adults.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Article
- Soluble fermentable dietary fiber attenuates age-related cognitive impairment via neuroimmune and antioxidant modulation: evidence from multilevel analyses in populations and aging mouse models.Frontiers in immunology · 2026Article
- The association between dietary fiber intake and cognitive function: mediating role of inflammatory markers.Frontiers in nutrition · 2025Article
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Authors and funding
8 authors.
Funding
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Abstract
Background: Emerging evidence suggests dietary fiber may prevent cognitive decline, but its dose-response relationship and underlying mechanisms remain unclear. This study investigates the non-linear association between dietary fiber intake and cognitive function in older adults and explores the mediating role of vitamin E. Methods: This cross-sectional analysis of nationally representative National Health and Nutrition Examination Survey (NHANES) Data from 2011 to 2014 included 2,713 adults aged ≥60 years. Dietary fiber intake was assessed using two 24-h dietary recalls. Cognitive function was evaluated using a comprehensive battery comprising three standardized assessments: the Digit Symbol Substitution Test (DSST) to measure processing speed, the Animal Fluency Test (AFT) to assess executive function, and a Consortium to Establish a Registry for Alzheimer's Disease (CERAD) subtest to evaluate memory performance. Composite Results: A J-shaped relationship between cognitive function and dietary fiber intake was identified using a two-piece-wise linear regression model. DSST scores reached a plateau at 29.65 g/day of fiber intake (likelihood ratio test Conclusion: Moderate dietary fiber intake is associated with optimal cognitive performance, largely mediated by vitamin E.
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