ArticleFrontiers in nutrition2025
Oral low dose of glutamine improved the spontaneous closure in patients with external duodenal fistula: a retrospective comparative study with propensity score matching.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Glutamine metabolism in health and disease.Signal transduction and targeted therapy · 2026Review
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7 authors.
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Abstract
Background: Spontaneous closure of external duodenal fistula (EDF) is associated with reduced gastrointestinal inflammation. Low-dose glutamine supplementation in the intestine can directly improve intestinal permeability and promote mucosal healing, potentially aiding fistula closure. This study investigates the effects of oral glutamine supplementation on EDF treatment outcomes. Methods: A retrospective cohort study was conducted from January 2019 to June 2024, including 104 adult patients with EDF. Based on the administration of low-dose (10 g/day) oral glutamine supplementation, patients were divided into a glutamine group ( Results: Spontaneous closure occurred in 28 patients (52%) in the glutamine group, compared to 21 patients (42%) in the non-glutamine group ( Conclusion: Glutamine supplementation may enhance spontaneous EDF closure and reduce hospital stay duration.
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